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Hypertension:日常活动量与不同血压水平人群死亡率的相关性

2019-11-16 QQY MedSci原创

如何确定对高血压患者心脏健康最大益处的运动量,一直都是一个挑战。Joseph等人开展一项研究探索日常体力活动水平与全因死亡率和心血管预后在不同血压水平上的相关性。在一项前瞻性心血管人群研究中,随机抽取了18 974名年龄在20到98岁之间的白人男性和女性。从体育活动问卷中收集自我报告的闲暇时间活动水平(I级:不活动;II级:少量活动;III级:中度-高强度活动)。血压分级:正常血压:<120

如何确定对高血压患者心脏健康最大益处的运动量,一直都是一个挑战。Joseph等人开展一项研究探索日常体力活动水平与全因死亡率和心血管预后在不同血压水平上的相关性。

在一项前瞻性心血管人群研究中,随机抽取了18 974名年龄在20到98岁之间的白人男性和女性。从体育活动问卷中收集自我报告的闲暇时间活动水平(I级:不活动;II级:少量活动;III级:中度-高强度活动)。血压分级:正常血压:<120/<80 mm?Hg;高血压前期:120–139/80–89 mm?Hg;I期高血压:140–159/90–99 mm?Hg;II期高血压:≥160/≥100 mm?Hg。



中位随访23.4±11.7年。在剂量反应模式中,对于所有水平血压的受试者,体力活动水平越高,全因死亡率越低。根据性别、年龄、吸烟状况、教育程度、糖尿病、既往心血管疾病、体重指数和日历时间等混杂因素进行调整后,该模式保持不变。与不活动相比,轻度活动和中/高强度活动的人群罹患I期高血压的风险比分别是0.78和0.69。对于所有血压水平的人群,心血管事件风险显著降低,且与体力活动的水平无关。

总而言之,在所有血压水平上,体力活动与全因死亡率呈负剂量反应模式。体力活动与心血管事件减少相关,但与活动强度无关。

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    2020-05-20 feather89
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1984277, encodeId=36b719842e701, content=<a href='/topic/show?id=4af8889533b' target=_blank style='color:#2F92EE;'>#血压水平#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88953, encryptionId=4af8889533b, topicName=血压水平)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Tue Jun 02 22:31:00 CST 2020, time=2020-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2039119, encodeId=8f972039119c0, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Fri Apr 03 06:31:00 CST 2020, time=2020-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1635519, encodeId=fec5163551923, content=<a href='/topic/show?id=54d965196db' target=_blank style='color:#2F92EE;'>#活动量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65196, encryptionId=54d965196db, topicName=活动量)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbc822488484, createdName=124987cdm33暂无昵称, createdTime=Thu Dec 05 04:31:00 CST 2019, time=2019-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728198, encodeId=b2bc1e2819816, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed May 20 22:31:00 CST 2020, time=2020-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837749, encodeId=d350183e7493a, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sun Mar 22 07:31:00 CST 2020, time=2020-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678961, encodeId=0ab316e896144, content=<a href='/topic/show?id=6339592095d' target=_blank style='color:#2F92EE;'>#日常活动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59209, encryptionId=6339592095d, topicName=日常活动)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=474e27711260, createdName=lily1625, createdTime=Sat Jun 27 18:31:00 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501413, encodeId=67dd1501413bc, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Mon Nov 18 11:31:00 CST 2019, time=2019-11-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=375456, encodeId=aee23e545699, content=谢谢了,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Sun Nov 17 07:26:38 CST 2019, time=2019-11-17, status=1, ipAttribution=)]
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    2019-11-17 txqjm

    谢谢了,学习

    0

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MRI显示以脑白质高信号为代表的皮层下微血管疾病与老年高血压患者的大脑功能减退有关。24小时平均收缩压(BP)水平患者的活动能力、白质疾病进展和认知功能有怎样的影响?研究人员开展一项前瞻性的、随机化研究,评估两个24小时平均收缩压水平对≥75岁的收缩期高血压患者的活动能力、白质疾病进展和认知功能的影响。MRI显示受试患者均有脑白质高信号病灶。将受试患者随机分至24小时平均收缩压≤130 mm Hg

Neurology:生存偏倚可解释aSAH后吸烟者和高血压患者生存率改善

由此可见,aSAH后,吸烟和高血压与较差的生存率有关。早期和相反的结果可能是由于危险因素指标较少和医院危险因素研究固有的生存偏倚所致,这些研究缺乏关于尸检证实的院外死亡的信息。

JAMA Netw Open:健康的胖子?来看看超重中国人的高血压高血糖风险

肥胖与多种代谢并发症有关,包括2型糖尿病、高血压、中风、抑郁症以及某些类型的癌症。不过,生活中也总有“看似健康的胖子”,虽然体重超标,但倒是没有“三高”。这些人是真的受眷顾,代谢功能能够抗住体重的压力,还只是处于过渡期,问题尚未暴露?

J Am Heart Assoc:国人家庭饮食习惯重男轻女!男士确诊高血压,家庭饮食习惯改善,女士患高血压则不然

对于高血压患者来说,饮食干预是非常重要的一种管理策略。大量证据表明,少吃盐、多吃含钾丰富的食物(水果、蔬菜、豆类)不仅有助于降压,还能降低心血管事件和死亡风险。

Hypertension:评价高血压心脏受损,可用4期法,右心受累预后最差!

日本研究人员在Hypertension杂志发表的一项研究表明,一种原本在主动脉瓣狭窄患者中建立的心脏受损分期法用于高血压患者,对长期预后也有很好的预测作用。

协和医院曾正陪教授:原醛症患病率可达5%~13%

从1952年“醛固酮”被认识到当前,人们对原醛症的认识发生了很多变化。在中国心脏大会(CHC)2019、深圳心血管健康和疾病防治高峰论坛上,北京协和医院曾正陪教授指出,过去认为原醛症是一种少见高血压类型,但实际上患病率要高很多。

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