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Nutrients:维生素对青光眼的影响-系统评价和meta分析

2018-03-18 cuiguizhong MedSci原创

荷兰马斯特里赫特大学医学中心眼科的Ramdas WD在Nutrients杂志上发表了一篇文章,介绍他们通过系统评价和meta分析来确定维生素与青光眼的关系。

荷兰马斯特里赫特大学医学中心眼科的Ramdas WD在Nutrients杂志上发表了一篇文章,介绍他们通过系统评价和meta分析来确定维生素与青光眼的关系。

具体实验策略是,在PubMed和Embase数据库中查找截至到2017年12月发表的关于维生素和青光眼的研究。记录维生素相关数据(评估方法)和青光眼评估类型和方法,对其特征和质量进行研究。在对一种营养素进行多项研究的情况下,进行meta分析。

结果他们共确定了629篇文章,其中36篇纳入系统研究。meta分析从940例开角型青光眼(OAG)病例和123,697例对照组中挑选5例进行研究。虽然异质性很高(I?= 51%),膳食维生素A的OR值[95%置信区间](OR [95%CI])为0.58,范围从0.37到0.91 ]。在排除了对异质性有显着贡献的研究之后,饮食维生素A对OAG的汇集的OR值 [95%CI]为0.45 [0.30-0.68](I 2 = 0%)。维生素B1、C和E与OAG之间没有显着关联,OR [95%CI]值分别为0.84 [0.47-1.51];、0.68 [0.38-1.22]、0.95 [0.75-1.19];)。然而,在排除异质性后,维生素C也显示出保护作用。特别是,这些维生素含量高的食物(例如深绿色蔬菜)对OAG具有良好的保护作用。

因此,他们认为,膳食摄入维生素A和C,对OAG具有有益的作用。然而,对维生素血液水平的研究结果表明,这与OAG没有明确的相关性。

原文出处:

Ramdas, W.D., J. Schouten, and C.A.B. Webers, The Effect of Vitamins on Glaucoma: A Systematic Review and Meta-Analysis. Nutrients, 2018. 10(3).

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

 

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    2018-12-30 一闲
  2. 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    2019-02-01 guojianrong
  3. 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    2018-03-19 huagfeg
  4. 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createdName=guojianrong, createdTime=Fri Feb 01 20:22:00 CST 2019, time=2019-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1444345, encodeId=3ebd1444345c1, content=<a href='/topic/show?id=3d9291459d1' target=_blank style='color:#2F92EE;'>#评价#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91459, encryptionId=3d9291459d1, topicName=评价)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fee5134542, createdName=huagfeg, createdTime=Mon Mar 19 15:22:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297583, encodeId=c2af29e583d4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Mon Mar 19 06:27:52 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297343, encodeId=9ddf29e343f3, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRk75KAEKrLGic0S0IvH1aNynsEFQWiaNKdtzvtwj2kafCoPg2icYVbrfBCFiaS74X1uEiaaTTY1H9Xyem/0, createdBy=cec11614828, createdName=chunjianf, createdTime=Sun Mar 18 08:26:44 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297321, encodeId=1d9929e321cb, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:19 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297233, encodeId=af0929e233e4, content=维生素对青光眼的影响-, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:14 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297232, encodeId=6e6329e23268, content=维生素对青光眼的影响-, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-19 121832a9m88暂无昵称

    学习了

    0

  5. 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createdName=guojianrong, createdTime=Fri Feb 01 20:22:00 CST 2019, time=2019-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1444345, encodeId=3ebd1444345c1, content=<a href='/topic/show?id=3d9291459d1' target=_blank style='color:#2F92EE;'>#评价#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91459, encryptionId=3d9291459d1, topicName=评价)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fee5134542, createdName=huagfeg, createdTime=Mon Mar 19 15:22:00 CST 2018, time=2018-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297583, encodeId=c2af29e583d4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, 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objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 chunjianf

    学习了.谢谢分享

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 大爰

    学习了谢谢分享!!

    0

  7. 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objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 ann y

    维生素对青光眼的影响-

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 ann y

    维生素对青光眼的影响-

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Sun Mar 18 00:40:08 CST 2018, time=2018-03-18, status=1, ipAttribution=)]
    2018-03-18 ann y

    维生素对青光眼的影响-

    0

  10. 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    2018-03-18 ann y

    维生素对青光眼的影响-

    0

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2018年1月,发表于《Nephrol Dial Transplant》上的一项研究表明,维生素K拮抗剂的使用与不同CHA2DS2-VASc评分的透析患者的死亡率的保护作用不相关。

东南大学医学院马根山等研究称,这种维生素竟然可预防对比剂肾病

对比剂肾病在临床并不少见,少用点对比剂和水化疗法是普遍认可的防治措施。近日,东南大学医学院马根山、唐庚等进行的Meta分析还显示,用点维生素,尤其是维生素C也有助于降低对比剂肾病的发生风险。

维C抗癌之前世今生

早年,人们将维C作为万能良药一样供奉,影响了几代人的健康观,感冒、口腔溃疡等等均服用维C。最早将维C引入我们大众生活的是两次获得诺贝尔奖的鲍林教授(Linus Pauling),他提出了维生素作用的新观点,尤其是主张超大剂量服用维生素C。

PNAS:惊喜!维生素B3或可治疗阿尔兹海默症

维生素B3是人体必需的13种维生素之一。去年,一项为期12年的研究证实,怀孕期间补充微生物B3或能预防严重出生缺陷。现在,科学家们又发现,维生素B3或许还可以治疗阿尔兹海默症,能减缓大脑认知、记忆功能的损伤。

JAMA:维生素及矿物质补充指南

维生素及矿物质补充指南

Am Heart J:心梗后大剂量服用多种维生素和矿物质可能有意外之喜

2018年1月,发表在《Am Heart J》的一项由于美国科学家进行的研究,在评估螯合疗法的随机试验(TACT)中,考察了大剂量口服多种维生素和矿物质的作用。

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