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The Key Regulator of Necroptosis, RIP1 Kinase, Contributes to the Formation of Astrogliosis and Glial Scar in Ischemic Stroke

Zhu, YM; Lin, L; Wei, C; Guo, Y; Qin, Y; Li, ZS; Kent, TA; McCoy, CE; Wang, ZX; Ni, Y; Zhou, XY; Zhang, HL

Zhang, HL (corresponding author), Soochow Univ, Jiangsu Key Lab Neuropsychiat Dis, Sch Publ Hlth, 199 Ren Ai Rd, Suzhou 215123, Jiangsu, Peoples R China.; Zhang, HL (corresponding author), Soochow Univ, Coll Pharmaceut Sci, Sch Publ Hlth,Lab Cerebrovasc Pharmacol, Jiangsu Key Lab Prevent & Translat Med Geriatr Di, 199 Ren Ai Rd, Suzhou 215123, Jiangsu, Peoples R China.

TRANSLATIONAL STROKE RESEARCH, ; ():

Abstract

Necroptosis initiation relies on the receptor-interacting protein 1 kinase (RIP1K). We recently reported that genetic and pharmacological inhibition o......

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