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Stroke:急诊科对房颤患者进行卒中预防益处如何?

2017-04-08 xing.T MedSci原创

由此可见,卒中高危的房颤患者在ED进行抗凝治疗不会增加出血风险,并有助于降低死亡率。

在急诊科(ED)就启动卒中预防的长期益处仍是未知的。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在分析房颤患者在急诊接受口服抗凝药治疗的长期安全性和益处。

研究人员在62个西班牙EDs对连续就诊的心房颤动患者进行了一项前瞻性、多中心的、观察性队列研究。临床变量可用以及在出院时给予血栓预防的处方的患者被纳入研究。出院后随访1年后,收集的数据包括预防血栓形成及其并发症、大出血和死亡等情况;研究人员采用一元和二元Logistic回归模型来评估风险。

研究人员招募了1162例患者,1024例(88.1%)患者根据CHA2DS2-VASc评分为高风险。在ED出院时,935例(80.5%)患者接受抗凝治疗,237例(55.2%)患者为接受抗凝治疗的新患者。在1年后,48例(4.1%)患者出现重大出血事件,151例(12.9%)患者出现死亡。在ED接受首次抗凝与大出血不相关(风险比为0.976;95%可信区间为0.294-3.236),但与死亡率下降相关(风险比为0.398;95%可信区间为0.231-0.686)。将主要临床和社会人口学特征、伴随抗血小板治疗或目的地(出院或入院)进行调整后,并不影响结果。

由此可见,卒中高危的房颤患者在ED进行抗凝治疗不会增加出血风险,并有助于降低死亡率。

原始出处:

Blanca Coll-Vinent,et al. Benefits of Emergency Departments’ Contribution to Stroke Prophylaxis in Atrial Fibrillation.Stroke. 2017. http://stroke.ahajournals.org/content/early/2017/04/07/STROKEAHA.116.014855

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    2017-04-11 jin321

    急诊太忙了,还是交给住院部啊

    0

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  4. 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  5. 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    2017-04-09 baihao215

    再一次印证性研究

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sat Apr 08 19:03:43 CST 2017, time=2017-04-08, status=1, ipAttribution=)]
    2017-04-09 往日如昨

    学习了谢谢分享

    0

  7. 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objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0a61971598, createdName=往日如昨, createdTime=Sun Apr 09 01:34:20 CST 2017, time=2017-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186035, encodeId=509618603520, content=签到学习了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/A3E53E62691178E2F18D7B999FD22131/100, createdBy=f44d2003846, createdName=Chongyang Zhang, createdTime=Sat Apr 08 21:00:43 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186026, encodeId=bf6518602653, content=厉害,学习啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sat Apr 08 20:02:58 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186020, encodeId=048718602052, content=学习,受益匪浅!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sat Apr 08 19:14:02 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186015, encodeId=94771860155c, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sat Apr 08 19:03:43 CST 2017, time=2017-04-08, status=1, ipAttribution=)]
    2017-04-08 Chongyang Zhang

    签到学习了很多

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sat Apr 08 20:02:58 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186020, encodeId=048718602052, content=学习,受益匪浅!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Sat Apr 08 19:14:02 CST 2017, time=2017-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=186015, encodeId=94771860155c, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sat Apr 08 19:03:43 CST 2017, time=2017-04-08, status=1, ipAttribution=)]
    2017-04-08 tanxingdoctor

    厉害,学习啦!

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Pw2csslt7CukWiabqiblnQAXaDEiaxhu025c3P0XshccTrbvGWBjKvnHIxbK3vqa80P7WGIFuicCFet97TicrNKpgB3TdabxP1vMh/0, createdBy=28851960965, createdName=榄枷檬, createdTime=Sat Apr 08 19:03:43 CST 2017, time=2017-04-08, status=1, ipAttribution=)]
    2017-04-08 执着追梦

    学习,受益匪浅!

    0

  10. 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    2017-04-08 榄枷檬

    谢谢分享

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