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CEBP:身高较高的绝经后女性,患癌风险明显增加

2013-07-26 林小春 MedSci原创

人们普遍认为,肥胖是癌症的重要风险因素。然而美国一项最新研究声称,个头高的女性,其患癌风险也高。美国耶希瓦大学研究人员25日在《癌症流行病学、生物标志和预防》杂志上报告说,他们对约14.5万名50岁至79岁的女性进行了12年的跟踪研究,其中近2.1万人在研究期间被确诊罹患一种或多种癌症。 研究人员发现,女性身高每增加10厘米,罹患黑素瘤、乳腺癌、卵巢癌、子宫内膜癌和结肠癌等癌症的风险增加13

人们普遍认为,肥胖是癌症的重要风险因素。然而美国最新一项前瞻性队列研究表明,个头高的女性,其患癌风险也高。而且很少研究关注这一点。

美国耶希瓦大学研究人员25日在《癌症流行病学、生物标志和预防》杂志上报告说,他们对约144,701名50岁至79岁的女性进行了12年的跟踪研究,其中近 20,928人在研究期间被确诊罹患一种或多种癌症。

研究人员发现,绝经期后的女性升高与肿瘤的风险为HR = 1.13(95% CI, 1.11–1.16),女性身高每增加10厘米,罹患黑素瘤、乳腺癌、卵巢癌、子宫内膜癌和结肠癌等癌症的风险增加13%至17%;而罹患肾癌、直肠癌和甲状腺癌等癌症风险增加23%至29%。

研究人员表示,他们共研究了19种癌症,研究中排除了年龄、体重、教育、抽烟、饮酒和激素疗法等影响因素。

针对这一结果,研究第一作者、耶希瓦大学爱因斯坦医学院的杰弗里·卡巴特表示:“我们很惊讶。我们的研究发现,更多的癌症是与身高而不是肥胖程度相关。这一研究的意义在于,影响身高的激素或其他生长因素可能也是癌症的风险因素。”

原始出处:

Geoffrey C. Kabat,Matthew L. Anderson,Moonseong Heo,et al.Adult Stature and Risk of Cancer at Different Anatomic Sites in a Cohort of Postmenopausal Women. Cancer Epidemiol Biomarkers Prev.Published OnlineFirst July 25, 2013; doi:10.1158/1055-9965.EPI-13-0305

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    2013-08-13 sjq027
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    2013-08-07 kljjma

    有的惊讶,还好我个子不高。

    0

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    2013-07-28 zxxiang

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