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JAHA:母乳喂养史与绝经后妇女卒中风险

2018-08-22 xing.T MedSci原创

由此可见,该研究的结果显示,在调整多发性卒中危险因素和生活方式变量后,绝经后妇女母乳喂养与卒中风险降低之间存在关联,并且呈剂量反应关系。

卒中是65岁及以上西班牙裔美国人和非西班牙裔黑人女性死亡的第三大原因。可以预防卒中的一个因素是母乳喂养,但是很少有研究评估母乳喂养与卒中之间的关系,以及这种关联是否因人种和民族有所而异。近日,血管疾病领域权威杂志JAHA上针对这一问题发表了一篇研究文章。

该研究的数据来自妇女健康倡议观察性研究,受试者随访至2010年;研究人员通过Cox回归模型估算了分娩后卒中调整后风险比

在妇女健康倡议观察性研究的80191名女性中,2699名(3.4%)女性参与者在12.6年的随访期间发生了卒中。基线时的平均年龄为63.7岁。58%的受试者(n=46699)报告进行过母乳喂养;83%的受试者为非西班牙裔白人,8%的受试者为非西班牙裔黑人,4%的受试者为西班牙裔,5%的受试者为其他人种/民族。调整了不可改变的潜在混杂因素后,与从未进行母乳喂养的女性相比,进行母乳喂养的女性发生卒中的风险降低23%(校正后风险比=0.77; 95%置信区间为0.70-0.83)。在非西班牙裔黑人女性中这种关联最强(校正后风险比=0.52; 95%置信区间为0.37-0.71)。此外,母乳喂养持续时间相对较短(1-6个月),卒中风险降低19%(校正后风险比=0.81; 95%置信区间为0.74-0.89)。这种关联在母乳喂养时间更长以及非西班牙裔白人和非西班牙裔黑人女性中更强(趋势P<0.01)。

由此可见,该研究的结果显示,在调整多发性卒中危险因素和生活方式变量后,绝经后妇女母乳喂养与卒中风险降低之间存在关联,并且呈剂量反应关系。

原始出处:


Lisette T. Jacobson.et al. Breastfeeding History and Risk of Stroke Among Parous Postmenopausal Women in the Women's Health Initiative.JAHA.2018. https://www.ahajournals.org/doi/full/10.1161/JAHA.118.008739

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    2018-08-24 zhaohui6731
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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
  5. 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time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340502, encodeId=fb4d34050233, content=26619192, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Fri Aug 24 09:15:18 CST 2018, time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340244, encodeId=c9713402449a, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Thu Aug 23 00:28:18 CST 2018, time=2018-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
    2018-08-24 villahu
  6. 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  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
    2018-08-24 zxxiang
  8. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
    2018-08-24 荒郊野树

    26619192

    0

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time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340502, encodeId=fb4d34050233, content=26619192, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Fri Aug 24 09:15:18 CST 2018, time=2018-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=340244, encodeId=c9713402449a, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18741984753, createdName=smartxiuxiu, createdTime=Thu Aug 23 00:28:18 CST 2018, time=2018-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
    2018-08-23 smartxiuxiu

    0

  10. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026135, encodeId=8a40102613582, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Aug 23 00:18:00 CST 2018, time=2018-08-23, status=1, ipAttribution=)]
    2018-08-23 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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尽管计划怀孕对WWE至关重要,但WWE中超过一半的怀孕属于非计划性。与WWoE相比,产妇年龄和SES差异可能导致WWE的比率更高。尽管有研究表明WWE母乳喂养的安全性,但WWE报告母乳喂养的比例较低。

[重复]JAMA Intern Med:母乳喂养半年以上 宝妈糖尿病风险减半

谈起母乳喂养的益处,大家可能都如数家珍,如增加新生儿免疫力使之免受感染和疾病的侵害、促进婴儿感觉和认知的发育、有助于母亲产后身体恢复和减少母亲产后抑郁的发生等。但既往研究表明,母乳喂养对女性慢性病的影响很小。

SCI REP:母乳喂养与近视

总之,天津市6-12岁儿童接受母乳喂养与近视风险降低有关。婴儿出生后前6个月的母乳喂养与更远的SER相关。此外,母乳喂养与近视屈光有关,但与AL无关,这种关联可能存在于儿童时期。

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