Baidu
map

Lancet Infect Dis:新冠肺炎家庭二次传播风险评估

2020-06-18 MedSci原创 MedSci原创

与非典病毒和中东呼吸综合征冠状病毒相比,新冠肺炎病毒的家庭传播能力更强,60岁以上老年人最易感染受到家庭传播。除发现和隔离病例外,还应及时对密切接触者进行追踪和隔离,防止病毒在潜伏期内继续传

截至2020年6月8日,全球报告的COVID-19病例已超过700万,死亡人数超过40万。近日研究人员采用统计传播模型,对广州市家庭与非家庭密切接触者SARS-CoV-2的二次发病率进行了评估。
 
本次研究为回顾性队列研究,使用了广州市疾病预防控制中心的新冠肺炎接触追踪数据库数据,估计家庭和非家庭接触者中COVID-19的发病率(定义为感染者将疾病传播给易感者的概率)。在分析中,研究人员考虑了两种不同的家庭接触定义:一种是家庭成员,另一种是近亲,如父母和岳父岳母,不考虑居住地址;另一种是住在同一地址,不考虑关系。研究人员评估了COVID-19病例在潜伏期内传播性和传染性的人口决定因素。
 
在2020年1月7日至2020年2月18日期间,研究人员追踪了195个不相关的亲密接触群体(215个初始病例、134个二级或三级病例和1964个未受感染的亲密接触者)。通过从这些组中确定家庭,假设平均潜伏期为5天,最长感染期为13天,并且没有病例隔离,当根据近亲定义家庭接触者时,家庭接触者的二次发病率为12.4%;当根据居住地址定义家庭联系人时为17.1%。与最大年龄组(60岁以上)相比,最小年龄组(<20岁; OR:0.23)和20-59岁成年人(OR:0.64)的家庭感染风险较低。本结果表明新冠肺炎潜伏期的传染性比症状期强,尽管差异不具有统计学意义(OR:0.61)。根据观察到的原发病例接触频率,估计广州地区的R0为0.5。如果没有隔离病例或接触者,当根据近亲定义家庭时,预测的本地R0为0.6。
 
研究发现,与非典病毒和中东呼吸综合征冠状病毒相比,新冠肺炎病毒的家庭传播能力更强,60岁以上老年人最易感染受到家庭传播。除发现和隔离病例外,还应及时对密切接触者进行追踪和隔离,防止病毒在潜伏期内继续传播。
 
原始出处:
 
 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1830699, encodeId=0065183069928, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 08:02:50 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013403, encodeId=91ef20134033b, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Sep 12 15:02:50 CST 2020, time=2020-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813723, encodeId=5e35813e23ae, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:01:44 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028202, encodeId=4050102820243, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033843, encodeId=a52d103384336, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
    2020-09-20 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1830699, encodeId=0065183069928, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 08:02:50 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013403, encodeId=91ef20134033b, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Sep 12 15:02:50 CST 2020, time=2020-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813723, encodeId=5e35813e23ae, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:01:44 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028202, encodeId=4050102820243, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033843, encodeId=a52d103384336, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1830699, encodeId=0065183069928, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 08:02:50 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013403, encodeId=91ef20134033b, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Sep 12 15:02:50 CST 2020, time=2020-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813723, encodeId=5e35813e23ae, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:01:44 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028202, encodeId=4050102820243, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033843, encodeId=a52d103384336, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
    2020-08-27 14818eb4m67暂无昵称

    学习了

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1830699, encodeId=0065183069928, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 08:02:50 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013403, encodeId=91ef20134033b, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Sep 12 15:02:50 CST 2020, time=2020-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813723, encodeId=5e35813e23ae, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:01:44 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028202, encodeId=4050102820243, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033843, encodeId=a52d103384336, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
    2020-06-18 公卫新人

    新冠肺炎,疫情何时才能消失

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1830699, encodeId=0065183069928, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Sep 20 08:02:50 CST 2020, time=2020-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2013403, encodeId=91ef20134033b, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Sat Sep 12 15:02:50 CST 2020, time=2020-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=813723, encodeId=5e35813e23ae, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=64245268311, createdName=14818eb4m67暂无昵称, createdTime=Thu Aug 27 08:01:44 CST 2020, time=2020-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028202, encodeId=4050102820243, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1033843, encodeId=a52d103384336, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Thu Jun 18 22:02:50 CST 2020, time=2020-06-18, status=1, ipAttribution=)]
    2020-06-18 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

相关资讯

新冠病毒潜伏期最长多久?近期两例达到27天和38天!

新冠肺炎超长潜伏期是否存在?2020年2月17日上午,广东省河源市公布一例确诊病例,患者从武汉坐火车回河源,于2月8日解除14天医学观察,6天后开始无明显诱因出现咳嗽,并最终确诊。另外,山东省日照市刘某因曾接触确诊病例,于1月20日和一家四口被隔离,期间无异常,然而在隔离结束10天后,刘某开始出现咳嗽、发热等症状,于2月15日确诊感染新冠肺炎。在此之前,四川省宜宾市便在2月11日通报了一位新冠肺炎

湖北副省长回应确诊病例大幅增加:潜伏期病人发病、检测加快

2月1日21时,湖北省人民政府召开新闻发布会,通报新冠肺炎疫情防控工作。发布会上,有记者向湖北省副省长杨云彦提问,为什么近期出现确诊病例大幅增加,在这种情况下有什么应对措施?杨云彦回应道,近三天,湖北全省新增病例都在1000例以上,维持在高位。杨云彦说,针对这个现象有四个方面的原因:第一,潜伏期病人陆续发病。根据专家的判断,新型冠状病毒最长的潜伏期可达14天,武汉市从23号起采取措施,减少人员的流

器官移植可成狂犬病毒感染来源

  据7月24/31日发表在《美国医学会杂志》上的一则研究披露,针对一个接触了浣熊狂犬病毒而致死的病例的源头所作的调查表明,该个体是通过18个月前的一次肾移植而得到该病毒的;这些发现提示,通过这一路径传播的狂犬病具有很长的潜伏期,而且尽管实体器官移植传播传染性脑炎是罕见的,但有必要开展进一步的教育以提高人们对此病的认识。 狂犬病毒会引起致死性脑炎(脑部炎症)且该病毒可通过组织或器官移植而传播。

Baidu
map
Baidu
map
Baidu
map