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NRR:葡萄籽提取物可减少视网膜神经节细胞的死亡

2013-11-06 伊文 eurekalert中文版

葡萄籽提取物视网膜神经节细胞
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许多视网膜神经疾病涉及视网膜神经节细胞死亡，而导致视网膜神经节细胞死亡的主要原因是氧化应激。最新研究表明，葡萄籽提取物可减轻氧化应激诱导的视网膜神经节细胞损害。由此，中国暨南大学/中国科学院苏国辉院士和Daxiang Lu教授领导的研究团队，通过RGC-5视网膜神经节细胞株和视网膜组织块实验证实，葡萄籽中富含的低聚原花青素可通过抑制细胞凋亡，拮抗视网膜神经节细胞氧化应激损伤。研究结果说明低

许多视网膜神经疾病涉及视网膜神经节细胞死亡，而导致视网膜神经节细胞死亡的主要原因是氧化应激。【原文下载】

最新研究表明，葡萄籽提取物可减轻氧化应激诱导的视网膜神经节细胞损害。由此，中国暨南大学/中国科学院苏国辉院士和Daxiang Lu教授领导的研究团队，通过RGC-5视网膜神经节细胞株和视网膜组织块实验证实，葡萄籽中富含的低聚原花青素可通过抑制细胞凋亡，拮抗视网膜神经节细胞氧化应激损伤。


研究结果说明低聚原花青素在治疗视网膜神经节细胞死亡引起青光眼和其他许多视神经疾病的视觉丧失方面具有潜在的应用价值。相关内容发表于《中国神经再生研究（英文版）》杂志2013年9月第25期。

原文出处：

Wang H, Zhang CJ, Lu D, Shu XM, Zhu LH, Qi RB, So KF, Lu DX, Xu Y. Oligomeric proanthocyanidin protects retinal ganglion cells against oxidative stress-induced apoptosis. Neural Regen Res. 2013;8(25):2317-2326.【原文下载】


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    2014-07-04 12498568m61暂无昵称

    #葡萄籽#

    0

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    2014-05-14 wumeihua100

    #视网膜神经节细胞#

    0

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    2014-06-28 徐岩

    #视网膜神经#

    0

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    2013-12-27 qilu_qi

    #神经节细胞#

    0

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    2013-11-08 zutt

    #视网膜#

    0

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