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NEJM:电子烟相关肺损伤住院或死亡患者特征研究

2020-04-23 MedSci原创 MedSci原创

慢性疾病,包括心脏、呼吸系统疾病以及精神疾病,在电子烟使用相关肺损伤住院患者中很常见

截至2020年1月7日,美国疾病控制和预防中心(CDC)共接到2558名非致命性和60名致命性电子烟使用相关肺损伤(EVALI)报告。
 
近日,在一项全国性的研究中,研究人员比较了EVALI致命病例和非致命病例的特征,以提高临床医生识别EVALI死亡风险的能力。卫生部门向疾控中心报告了EVALI病例的病历摘要和病人访谈的数据。研究人员还提供了三例因EVALI死亡的患者的病例报告,以分析这些患者共同的临床特征。
 
致命或非致命性EVALI病例的大多数患者为男性(分别为32/60 [53%]和1666/2498 [67%])。 非西班牙裔白人(分别占39/49[80%]和1104/1818[61%])的致死或非致命病例比例高于其他种族或族裔群体。35岁及以上(44/60 [73%])的死亡病例比例高于35岁以下,但35岁及以上(551/2514 [22%])的非死亡病例比例较低。对于已有病史患者,患有哮喘病史(13/57 [23%] vs 102/1297 [8%])、心脏病病史(26/55 [47%] vs 115/1169 [10%])或精神疾病(32/49 [65%]vs575/1398 [41%])患者的死亡病例比例高于非致命病例。50例死亡病例中有26例(52%)有肥胖症。半数死亡病例(25/54[46%])在住院或死亡前在门诊就诊。
 
研究发现,慢性疾病,包括心脏、呼吸系统疾病以及精神疾病,在电子烟使用相关肺损伤住院患者中很常见。
 
原始出处:
 
Angela K. Werner et al. Hospitalizations and Deaths Associated with EVALI. N Engl J Med, April 22, 2020.

 

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    2020-04-25 tastas
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1397958, encodeId=9956139e958e4, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503330, encodeId=7f6915033301e, content=<a href='/topic/show?id=67a7821250e' target=_blank style='color:#2F92EE;'>#肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82125, encryptionId=67a7821250e, topicName=肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=05329610584, createdName=tastas, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569952, encodeId=7d771569952fd, content=<a href='/topic/show?id=5f24e007361' target=_blank style='color:#2F92EE;'>#电子烟相关肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70073, encryptionId=5f24e007361, topicName=电子烟相关肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=841d15610664, createdName=lhlxtx, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623147, encodeId=d448162314e59, content=<a href='/topic/show?id=e3935305e39' target=_blank style='color:#2F92EE;'>#患者特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53057, encryptionId=e3935305e39, topicName=患者特征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=450a20505925, createdName=guojianrong, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382118, encodeId=807438211848, content=新冠肺炎吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Apr 23 23:52:04 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382115, encodeId=f960382115ec, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Thu Apr 23 23:02:44 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035246, encodeId=7bb710352468c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 23 21:52:28 CST 2020, time=2020-04-23, status=1, ipAttribution=)]
    2020-04-23 lovetcm

    新冠肺炎吧

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1397958, encodeId=9956139e958e4, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503330, encodeId=7f6915033301e, content=<a href='/topic/show?id=67a7821250e' target=_blank style='color:#2F92EE;'>#肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82125, encryptionId=67a7821250e, topicName=肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=05329610584, createdName=tastas, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569952, encodeId=7d771569952fd, content=<a href='/topic/show?id=5f24e007361' target=_blank style='color:#2F92EE;'>#电子烟相关肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70073, encryptionId=5f24e007361, topicName=电子烟相关肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=841d15610664, createdName=lhlxtx, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623147, encodeId=d448162314e59, content=<a href='/topic/show?id=e3935305e39' target=_blank style='color:#2F92EE;'>#患者特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53057, encryptionId=e3935305e39, topicName=患者特征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=450a20505925, createdName=guojianrong, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382118, encodeId=807438211848, content=新冠肺炎吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Apr 23 23:52:04 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382115, encodeId=f960382115ec, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Thu Apr 23 23:02:44 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035246, encodeId=7bb710352468c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 23 21:52:28 CST 2020, time=2020-04-23, status=1, ipAttribution=)]
    2020-04-23 qingfengqishi5

    学习了,学习了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1397958, encodeId=9956139e958e4, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503330, encodeId=7f6915033301e, content=<a href='/topic/show?id=67a7821250e' target=_blank style='color:#2F92EE;'>#肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82125, encryptionId=67a7821250e, topicName=肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=05329610584, createdName=tastas, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1569952, encodeId=7d771569952fd, content=<a href='/topic/show?id=5f24e007361' target=_blank style='color:#2F92EE;'>#电子烟相关肺损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70073, encryptionId=5f24e007361, topicName=电子烟相关肺损伤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=841d15610664, createdName=lhlxtx, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1623147, encodeId=d448162314e59, content=<a href='/topic/show?id=e3935305e39' target=_blank style='color:#2F92EE;'>#患者特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53057, encryptionId=e3935305e39, topicName=患者特征)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=450a20505925, createdName=guojianrong, createdTime=Sat Apr 25 09:52:28 CST 2020, time=2020-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382118, encodeId=807438211848, content=新冠肺炎吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Thu Apr 23 23:52:04 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=382115, encodeId=f960382115ec, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Thu Apr 23 23:02:44 CST 2020, time=2020-04-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035246, encodeId=7bb710352468c, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Apr 23 21:52:28 CST 2020, time=2020-04-23, status=1, ipAttribution=)]
    2020-04-23 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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1月不减肥,2月徒伤悲、3月徒伤悲……终于,3月23日,《肥胖》拉响4月肥胖警报。其中精选出的3篇论文分别从心理健康、儿童肥胖和行为失调等方面,探讨了肥胖问题。

干细胞移植会成为肥胖症的治疗良药吗?

贝鲁特阿拉伯大学(Beirut Arab University,BAU)健康科学学院的一组科研人员通过研究脂肪衍生MSCs(AD-MSCs)对肥胖和相关并发症的影响和建立可行性动物模型,以证明其对人类临床治疗的效果。

间充质干细胞治疗2型糖尿病和肥胖症

一项由上海第九人民医院普通外科和上海交通大学医学院普通外科科研人员完成的研究显示,脂肪组织来源的间充质干细胞(ADSCs)移植能够改善代谢平衡,并减少动物模型中的炎症反应。

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