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Eur Respir J:户外交通尾气以及污染空气会提高患哮喘的风险

2018-04-10 佚名 “细胞”微信号

根据最近发表在《European Respiratory Journal》杂志上的一篇文章,长期暴露于街道公共交通以及臭氧环境中会提高人们患哮喘的风险。

根据最近发表在《European Respiratory Journal》杂志上的一篇文章,长期暴露于街道公共交通以及臭氧环境中会提高人们患哮喘的风险。

这项研究表明户外空气污染与成年人患哮喘之间的相关性。

同时,该研究通过检测8-异前列烷(一种可以通过呼吸进入人体内,被认为是造成肺脏以及组织损伤的生物标志物)的含量,为两者之间的相关性提供了内在机制的解释。

该研究的主要作者,来自法国健康医学研究所的Anais Havet称:"我们早已知道短期暴露于污染的空气环境中会提高哮喘的严重程度,住院几率以及用药几率,但长期的暴露于哮喘之间的相关性研究还不够充分。对此,我们希望能够更好地理解两者之间的生物学联系"。

通过对法国境内的608名成年人(其中240名患有哮喘,剩余人群没有患有呼吸道疾病)进行追踪调查,估测了长期暴露在高度拥挤的公共交通环境以及臭氧环境中对人们哮喘症状的影响。

此外,作者还研究了长期暴露于户外污染空气环境、8-异前列烷的呼出量以及哮喘的严重程度之间的相关性。结果显示,高水平的8- 异前列烷会提高呼吸道的反应活性,从而提高粘液的分泌量以及呼吸道肌肉的收缩性,使得人们出现呼吸困难现象。

同时,作者利用无创手段检测了参与者呼出的气体中8-异前列烷的含量。

结果表明,高度拥挤的公共交通环境、臭氧环境以及8-异前列烷的含量会提高哮喘的患病风险。

原始出处:

Havet A,et al.Outdoor air pollution, exhaled 8-isoprostane and current asthma in adults: the EGEA study.Eur Respir J. 2018 Apr 4;51(4). pii: 1702036.

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    2018-04-12 yuandd
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    2018-04-10 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-04-10 医者仁心5538

    学习了.大力加强污染治理

    0

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