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Crit Care:右心室损伤对急性呼吸窘迫综合征患者死亡率的影响

2021-05-21 MedSci原创 MedSci原创

在这项纳入了1861名ARDS患者的系统回顾和荟萃分析中,RV损伤与患者总体和短期死亡率增加显著相关。

先前的研究发现急性呼吸窘迫综合征(ARDS)患者右心室(RV)损伤的发病率各异,并且其与患者的临床结局相关。

近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,在这项系统回顾和荟萃分析中,研究人员旨在探究RV损伤对ARDS患者死亡率的影响。

研究人员检索了Medline、Embase和对照试验的Cochrane登记中心,以确定探究了RV损伤与患者死亡率之间关系的研究。两位作者独立评估了研究是否符合纳入标准,并提取了所选患者和研究的特征和结局。在纳入研究中,经胸超声心动图(TTE)、经食道超声心动图(TEE)和PAC(肺动脉导管)用于诊断RV损伤。该分析的主要结局是ARDS患者的死亡率与RV损伤之间的关联。该分析报告的总死亡率为重症监护病房(ICU)死亡率、院内死亡率或90天内死亡率,短期死亡率定义为ICU死亡率、院内死亡率或30天内死亡率。

合并的死亡率

这项荟萃分析纳入了9项研究(N=1861例患者)。RV损伤包括RV功能障碍,伴有血流动力学损害的RV功能障碍,RV衰竭或急性肺心病,占21.0%(391/1861)。在汇总荟萃分析中,ARDS患者伴有RV损伤与总体死亡率(OR为1.45,95%CI为1.13-1.86,p=0.003,I2=0%)以及较短长期死亡率(OR为1.48,95%CI为1.14–1.93,p=0.003,I2=0%)升高显著相关。

由此可见,在这项纳入了1861名ARDS患者的系统回顾和荟萃分析中,RV损伤与患者总体和短期死亡率增加显著相关。

原始出处:

Ryota Sato.et al.The impact of right ventricular injury on the mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis.Critical Care.2021.https://ccforum.biomedcentral.com/articles/10.1186/s13054-021-03591-9

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    2021-06-15 shinwadd

    学习啦

    0

  3. 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createdAvatar=https://img.medsci.cn/20210524/0456f89e128a46948e578a75312c8d3c/e466bb6c0b644e8196e18e045a30a0f0.jpg, createdBy=1c165082954, createdName=橙子味的馒头, createdTime=Fri May 21 22:54:45 CST 2021, time=2021-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=967617, encodeId=6c5796e61715, content=学习好资料, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210521/1a91420096a84568816b2b28b4b05f3a/5f0ed6b74c6148bfacd30e54961031c9.jpg, createdBy=11d75183225, createdName=S宋宋S, createdTime=Fri May 21 22:32:10 CST 2021, time=2021-05-21, status=1, ipAttribution=)]
    2021-05-24 skywalk3004

    学习

    0

  4. 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May 23 13:11:42 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1582284, encodeId=3361158228463, content=<a href='/topic/show?id=e46f396832b' target=_blank style='color:#2F92EE;'>#呼吸窘迫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39683, encryptionId=e46f396832b, topicName=呼吸窘迫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=22be16898890, createdName=12498cf9m40(暂无昵称), createdTime=Sun May 23 13:11:42 CST 2021, time=2021-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=967621, encodeId=f3be96e62137, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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    2021-05-24 tanxingdoctor

    谢谢啦

    0

  5. 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  6. 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  7. 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  8. 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    2021-05-21 橙子味的馒头

    学习了

    0

  10. 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