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“DNA之父”詹姆斯·沃森教授谈抗癌新策略!2018深圳国际精准医疗峰会精彩大放送!

2018-03-18 佚名 生物探索

<!--ewebeditor:page title=""--> <div>DNA双螺旋结构发现者、诺贝尔生理学或医学奖得主、美国科学院院士、美国冷泉港实验室终身荣誉主任、深圳市科技专家委员会高级顾问、乐土科学总顾问、乐土沃森生命科技中心终身名誉主席詹姆斯·沃森教授此次再临中国,而作为沃森教授本次重磅行程之一的2018深圳国际精准医疗峰会已于3月16隆重举行!本届峰会以“肿瘤检测与治疗的精准医学”主题进行深入探讨和交流”为主题,邀请了中外科学院院士、知名教授、<a class="channel_keylink" href="http://edu.medsci.cn/course/search.do?w=%E4%B8%B4%E5%BA%8A" target="_blank">临床</a>专家等嘉宾,围绕肿瘤、<a class="channel_keylink" href="//m.capotfarm.com/article/list.do?q=%E5%B9%B2%E7%BB%86%E8%83%9E">干细胞</a>、聚集诱导发光基团(AIEgens)、小分子核糖核酸(miRNA

DNA双螺旋结构发现者、诺贝尔生理学或医学奖得主、美国科学院院士、美国冷泉港实验室终身荣誉主任、深圳市科技专家委员会高级顾问、乐土科学总顾问、乐土沃森生命科技中心终身名誉主席詹姆斯·沃森教授此次再临中国,而作为沃森教授本次重磅行程之一的2018深圳国际精准医疗峰会已于3月16隆重举行!本届峰会以“肿瘤检测与治疗的精准医学”主题进行深入探讨和交流”为主题,邀请了中外科学院院士、知名教授、临床专家等嘉宾,围绕肿瘤、干细胞、聚集诱导发光基团(AIEgens)、小分子核糖核酸(miRNA)等精准医学领域的热门展开探讨。

3月16日上午,为庆祝“深圳乐土沃森生命科技中心”启动,交流探讨精准医学在肿瘤防治中的最新应用;引进高端人才和产业项目,促进诺贝尔奖科学家、院士在深圳大鹏建立研究院和实验室,推动生命科技与医疗健康产业发展,由深圳市卫生和计划生育委员会、南方科技大学、深圳市乐土精准医疗科技有限公司联合主办的2018深圳国际精准医疗峰会正式拉开帷幕。大鹏新区党工委委员、综合办公室主任王继良,詹姆斯·沃森教授,美国科学院院士、美国纪念斯隆-凯特琳癌症医院教授Dinshaw Patel,美国科学院院士、哈佛大学医学院讲座教授吴皓,中国科学院院士、复旦大学生物医学研究院执行院长、中科院上海生命科学研究院研究员徐国良,中国科学院院士、香港科技大学讲座教授、华南理工大学-香港科技大学联合研究院院长唐本忠,南方科技大学校长陈十一,国家科技成果转化引导基金理事长、南科大乐土精准医学研究院理事长马蔚华,乐土投资集团董事长刘如银等重磅嘉宾出席了开幕式。


图 2018深圳国际精准医疗峰会现场

峰会伊始,由大鹏新区党工委委员、综合办公室主任王继良致欢迎辞

王继良委员代表大鹏新区党工委、管委会对大会的召开表示热烈的祝贺,对远道而来的各位专家、学者表示热烈的欢迎和崇高的敬意!今天,国际生命科技中心项目在大鹏新区顺利启动,这标志着诺贝尔生理学或医学奖得主詹姆斯·沃森先生带来的团队及研究机构正式落户深圳国际生物谷,对深圳国际生物谷建设成为国际领先的创新中心具有重要的示范和引领作用。本届峰会的主题是肿瘤检测与治疗的精准医学,推动这一领域的快速发展需要大批优秀的科学家、医学专家的研究探索,需要有社会责任感的企业大量的资本投入,需要政府好的政策,搭建好的平台,大鹏新区愿意为相关领域的科学研究提供最好的服务平台,并激励创造一流的投资营商环境,全力推动生命健康产业聚焦发展。王继良委员真诚地希望今天专家、学者在今天的峰会上能够充分交流学术、碰撞思想,享受科学盛筵,也真诚地希望各位能够带领推荐更多生命科学产业落户大鹏,与深圳国际生物谷一起奋斗成长。王继良委员在此预祝本次峰会圆满成功!


图 王继良委员致欢迎辞

国家科技成果转化引导基金理事长、南科大乐土精准医学研究院理事长、会议组委会主席马蔚华先生致辞

马蔚华先生认为,2018深圳国际精准医疗峰会和以往的峰会不同的地方就是,这一天乐土的项目(乐土沃森生命科技中心)已经在此扎根落地了。深圳乐土沃森生命科技中心的启动,表明沃森先生已经确定把他的实验室落户深圳,这件事对引领亚太地区生命科学发展的潮流,对于打造国际一流标杆的生命科技转化中心,对于带动现代精准医疗的传播,推动世界生命科学的传承具有非常重要的意义。因此,这次峰会的举办不但是庆祝深圳乐土沃森生命科技中心的启动,更是深圳生命科学领域的一件大事,也是深圳面向全球发展精准医疗的一次创新性的实践,有助于促进行业的国际交流与合作,开辟中国生命科学发展的一个新的阶段。为此,马蔚华理事长代表南科大乐土精准医学研究院向沃森先生,向到会的各位嘉宾表示热烈的欢迎。本届峰会以肿瘤检测与治疗的精准医学为主题,将围绕肿瘤干细胞聚集有道发光基因小分子核糖核酸等精准医学领域的热门话题,重点课题展开深入的讨论,这将是一个中西交流互动的平台,也是一场医学思维火花碰撞的盛筵,是一次科学发展的机缘。

乐土沃森生命科技中心落户在深圳应该是天时地利人和。所谓天时,国家正在为实现人们生活美好的需求勾划到健康的规划,而且在一步一步地落实这个规划,这是一个非常好的契机。地利就是深圳,这是中国改革开放的一块热土,有着良好改革的新环境和人才的区委优势,无论是体制机制还是经济的实力都是我们精准医疗发展的乐土。作为乐土精准医疗的参与者,回顾过去这一年多所取得巨大的成绩,未来还要继续汇聚全球的智慧,整合国际尖端的科技资源,打造深圳生命科学研究的硅谷,实现“产、学、研、医、会”良性互动,共建社会一流的产业基地园和精准医疗的创新中心。


图 马蔚华理事长致辞

南方科技大学校长陈十一致辞

陈十一校长首先对于峰会召开致以衷心的祝贺,并对远道而来的各位国际专家、嘉宾致以最热烈的欢迎和最诚挚的谢意。本次峰会以肿瘤检测与治疗的精准医学为主题,是一次生命科技成果展示的峰会,除了交流精准医疗,尤其是肿瘤检测和治疗领域的最新发展,还是一次集聚人才,推动创新,促进产学研结合的大会。会议期间深圳乐土沃森生命科技中心正式启动,这个科技中心的落地是深圳乃至中国生命科技领域的一个里程碑式的事件。借此机会,陈十一校长非常高兴地宣布,3月17日詹姆斯·沃森先生将正式受聘为南方科技大学的荣誉教授,并与南科大师生共飨一场科学与人生的思想盛筵。

2017年南科大与乐土联合建立南科大乐土精准医学研究院,在资金、人才等方面结合双方的资源和优势,共同推动精准医学在深圳和中国的发展,目前这个研究院正在肿瘤与妊娠期糖尿病等方面,积极与深圳第二人民医院北京大学深圳医院等开展深度合作。陈校长表示,衷心希望各位专家在本次的峰会上交流,碰撞出思想的火花,推动精准医疗在中国更好、更快地发展。同时也邀请各位专家和有识之士,能够积极帮助南科大和乐土沃森生命科技中心,参与到人类健康事业的工作中来。希望大家能够把梦想汇聚在一起,从创新之都深圳出发,鹏程万里,走向世界。


图 陈十一校长致辞

紧接着,詹姆斯·沃森教授开始了本次大会的主题演讲。

沃森教授表示,很高兴来到这里能够见到各位,同时能够加入到精准医疗的峰会当中,希望大家应该要不断地在科学研究领域思考癌症,并且花更多的时间来攻克癌症。之前特别提到的在早期的研究当中,有很多癌症治疗的方法,前期治疗的手段,相信还需要数年的研究和突破我们才能够真正的完成对于癌症的了解和治疗,彻底实现攻破癌症的目标。在癌症治疗上不仅仅想做到患者寿命的延伸,更想做的是对癌症的治愈。为什么癌症治愈那么困难呢?主要的因为是癌细胞和DNA之间的关系。接下来,沃森教授就和大家分享了如何通过清除癌细胞抗氧化物来治愈癌症。

沃森教授还认为,在我们现有的癌症治疗的疗法中,最关键的一点是能够真正完成癌细胞表面抗氧化物的清除,特别是如何通过自然产物将其进行清除。沃森教授相信抗氧化物的清除程度越高,我们能够治愈癌症的程度就越高。因此,沃森教授希望能够建立像乐土沃森生命科技中心这样的研究中心,帮助我们寻找到有效的科学路径,最终到达成功的彼岸,这也是他此次来到深圳建立这个研究中心的目的。癌症的研究到目前这个时间点,对于很多人来说并不是特别的有效,如果没有办法达到精准医疗,那么目前市面上所使用的癌症治疗方法就不适用于某些患者。但是在深圳建立乐土沃森生命科技中心和相关实验室,就是希望能够为癌症病人寻找到个性化定制的治疗癌症的方法,能够让更多的患者真正有机会实现个性化的诊断和治疗。他表示希望能够和大家共同携手,带来新的癌症治疗方法,或者是带来更多的药物,更好的治疗手段来满足个性化的发展,他相信乐土沃森生命科技中心通过大家共同的合作,不断的努力,最终的技术能够引领全球,能够造福人类。


图 沃森教授发表大会主题演讲

下一个环节,是北京奥维森基因科技公司与乐土投资集团的签约仪式,由奥维森创始人、CEO文洁女士与乐土刘如银董事长签署战略合作协议。


图 签约仪式

精彩纷呈、亮点频出的开幕式结束,接下来开展的是围绕“肿瘤检测与治疗的精准医学”主题的学术论坛。

首先发表演讲的是美国科学院院士、纪念斯隆-凯特琳癌症中心教授Dinshaw Patel。

演讲主题:Anti-CRISPR Proteins Targeting Cas9 and  Cascade  Complexes

图 Dinshaw Patel院士发表演讲

中国科学院院士、复旦大学生物医学研究院执行院长、中科院上海生命科学研究院研究员徐国良发表演讲,这是徐国良院士最近十几年来一直在做的研究工作,尽管进展是缓慢的,但徐国良院士分享了一些尚未发表,还在进行的研究。

演讲主题:DNA的酶促氧化在动物发育过程中的调控作用

图 徐国良院士发表演讲

复旦大学特聘教授、中山医院临床医学研究院执行院长王向东发表演讲,王向东教授主要谈了如何利用DNA的异质性建立新的疾病治疗策略。

演讲主题:Tumor Heterogeneity and Therapeutic Strategy

图 王向东教授发表演讲

纽约州立大学石溪分校终身教授、临床转化实验室主任鞠景芳发表演讲。他分享了微小RNA在癌症抗药性产生过程中的作用,以及微小RNA为主的结直肠癌治疗方法。

演讲主题:The development of miRNA based therapeutics for colorectal cancer

图 鞠景芳教授发表演讲

中国科学院院士、香港科技大学讲座教授、华南理工大学-香港科技大学联合研究院院长唐本忠发表演讲。唐本忠院士分享了诱导聚集发光分子的发光原理,及其在生命科学和肿瘤治疗领域的应用。AIE分子是是一种很神奇的疏水性分子,这种分子一聚集就开始发光,聚集越多光越强。唐本忠院士因在AIE分子方面的重磅成果,荣获了包括国家科技一等奖等重要奖项。

演讲主题:Applications of AIEgens in Life Science and Tumor Theranostics

图 唐本忠院士发表演讲

美国科学院院士、哈佛大学医学院讲座教授吴皓发表演讲。

演讲主题:Cryo-EM structures of inflammasomes for potential therapeutic intervention of human diseases

图 吴皓院士发表演讲

新加坡国立大学生物化学系主任、教授Markus Wenk发表演讲。

演讲主题:Towards individualized lipidomic tracking

图Markus Wenk教授发表演讲

华东理工大学***特聘教授杨弋发表演讲。

演讲主题:Visualizing and Targeting Cancer Cell Redox Metabolism


图 杨弋教授发表演讲

新加坡国立大学副教授、深圳华谱泰仕生物公司首席科学家章勇良发表演讲,章勇良教授主要讲了以DUSP10蛋白为靶点,开发新型的癌症治疗策略。DUSP10是T细胞中的一种JNK磷酸酶,在先天性和获得性免疫调节中均发挥重要作用,在临床应用上可作为一种识别癌症易感人群的生物标记物。

演讲主题:Target DUSP 10 for development of novel cancer therapy


图 章勇良教授发表演讲

各位嘉宾精彩的演讲完毕,2018深圳国际精准医疗峰会完美收官!

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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Mar 26 00:01:18 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299385, encodeId=bf15299385c0, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sun Mar 25 01:21:13 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299236, encodeId=54b3299236c3, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Mar 24 09:55:30 CST 2018, time=2018-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298855, encodeId=ef472988552f, content=学习.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Fri Mar 23 06:49:27 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298766, encodeId=8923298e66fd, content=学习学习学习., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 23 00:00:42 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298190, encodeId=a9522981908f, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Mar 21 05:31:46 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-04-13 执着追梦

    学习.谢谢分享

    0

  2. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Mar 26 00:01:18 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299385, encodeId=bf15299385c0, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sun Mar 25 01:21:13 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299236, encodeId=54b3299236c3, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 23 00:00:42 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298190, encodeId=a9522981908f, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Mar 21 05:31:46 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-04-12 执着追梦

    学习.谢谢分享

    0

  3. 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likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Mar 24 09:55:30 CST 2018, time=2018-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298855, encodeId=ef472988552f, content=学习.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Fri Mar 23 06:49:27 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298766, encodeId=8923298e66fd, content=学习学习学习., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 23 00:00:42 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298190, encodeId=a9522981908f, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Mar 21 05:31:46 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-04-08 执着追梦

    学习.谢谢分享

    0

  4. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-03-26 jihuaijun1112

    学习学习学习

    0

  5. 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    2018-03-25 jihuaijun1112

    学习学习学习

    0

  6. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-03-24 大爰

    学习了谢谢分享!!

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Mon Mar 26 00:01:18 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299385, encodeId=bf15299385c0, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Sun Mar 25 01:21:13 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299236, encodeId=54b3299236c3, content=学习了谢谢分享!!, beContent=null, objectType=article, channel=null, level=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 23 00:00:42 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298190, encodeId=a9522981908f, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Mar 21 05:31:46 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-03-23 执着追梦

    学习.谢谢分享

    0

  8. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Fri Mar 23 00:00:42 CST 2018, time=2018-03-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298190, encodeId=a9522981908f, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed Mar 21 05:31:46 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-03-23 jihuaijun1112

    学习学习学习.

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298162, encodeId=1e7c2981622c, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzR8ylhYfiaoAUx2BsaYHVia1IKhG3Cg8CT84rBrn6iaVRkyAibJxBcLEXabOQ5p19vWgDe34ib5ErxNgx/0, createdBy=8a701629084, createdName=jihuaijun1112, createdTime=Wed Mar 21 00:01:38 CST 2018, time=2018-03-21, status=1, ipAttribution=)]
    2018-03-21 三生有幸9135

    学习一下谢谢分享

    0

  10. 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    2018-03-21 jihuaijun1112

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