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Nat Med:新型微芯片可快速诊出1型糖尿病

2014-07-24 伊文 cnBeta

相信说到糖尿病,大家一定不会感到陌生,但估计有些人并不了解糖尿病也分类型--1型糖尿病和2型糖尿病。其中,1型糖尿病无法产生或只能产生极为少量的胰岛素,而2型糖尿病则能产生胰岛素,很显然,这两种类型的糖尿病治疗方法并不相同,所以对于人们来说,确诊患的是1型还是2型至关重要。 为此,来自斯坦福大学的Brian Feldman博士于日前研发了一种可快速对糖尿病类型做出判断的微芯片。据介绍

相信说到糖尿病,大家一定不会感到陌生,但估计有些人并不了解糖尿病也分类型--1型糖尿病和2型糖尿病。其中,1型糖尿病无法产生或只能产生极为少量的胰岛素,而2型糖尿病则能产生胰岛素,很显然,这两种类型的糖尿病治疗方法并不相同,所以对于人们来说,确诊患的是1型还是2型至关重要。

为此,来自斯坦福大学的Brian Feldman博士于日前研发了一种可快速对糖尿病类型做出判断的微芯片。据介绍,该微芯片通过确认病人血液中是否存在抗体来判定其得的究竟是1型还是2型的糖尿病。

而在传统诊断方法下,相关测试现必须要由经过特别训练的专业人员在实验室内进行,他们需要用到辐射材料、花费好几天时间得到实验结果,而且检测一次的费用也不低。

按照传统观念,1型糖尿病大多在青少年当中发病,而2型糖尿病主要集中在成年人。不过近几年,由于肥胖问题,越来越多的青少年也患上了2型糖尿病。这也是Fedlman博士要研发这么一款芯片的原因所在。

现在,人们不需要进行非常专业的训练就能在几分钟得到检测结果。据了解,该芯片的造价只需20美元,最多可重复使用15次。另外,待测者只需提供一滴血液即可。每块芯片的玻璃板上都镀上了一层纳米级别的金粒子阵列。它们的荧光信号将在遇到抗体的时候变强。

原始出处:

Zhang B, Kumar RB, Dai H, Feldman BJ.A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes.Nat Med. 2014 Jul 13. doi: 10.1038/nm.3619.

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    2015-04-11 x35042875

    糖尿病肾病进展风险的关系没有发现。

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=20683, encodeId=25412068349, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:28:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880195, encodeId=1477188019595, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Apr 22 05:00:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458901, encodeId=291214589012d, content=<a href='/topic/show?id=53cc8691532' target=_blank style='color:#2F92EE;'>#芯片#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86915, encryptionId=53cc8691532, topicName=芯片)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8bf76117088, createdName=lixiaol, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606247, encodeId=c992160624e8b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10623, encodeId=1d91106230c, content=关键如何应用于临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=123.150.123.159, createdTime=Fri Jul 25 20:33:00 CST 2014, time=2014-07-25, status=1, ipAttribution=)]
    2015-04-22 liye789132251
  3. [GetPortalCommentsPageByObjectIdResponse(id=20683, encodeId=25412068349, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:28:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880195, encodeId=1477188019595, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Apr 22 05:00:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458901, encodeId=291214589012d, content=<a href='/topic/show?id=53cc8691532' target=_blank style='color:#2F92EE;'>#芯片#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86915, encryptionId=53cc8691532, topicName=芯片)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8bf76117088, createdName=lixiaol, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606247, encodeId=c992160624e8b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10623, encodeId=1d91106230c, content=关键如何应用于临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=123.150.123.159, createdTime=Fri Jul 25 20:33:00 CST 2014, time=2014-07-25, status=1, ipAttribution=)]
    2014-07-26 lixiaol
  4. [GetPortalCommentsPageByObjectIdResponse(id=20683, encodeId=25412068349, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:28:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1880195, encodeId=1477188019595, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Wed Apr 22 05:00:00 CST 2015, time=2015-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1458901, encodeId=291214589012d, content=<a href='/topic/show?id=53cc8691532' target=_blank style='color:#2F92EE;'>#芯片#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86915, encryptionId=53cc8691532, topicName=芯片)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8bf76117088, createdName=lixiaol, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1606247, encodeId=c992160624e8b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Jul 26 01:00:00 CST 2014, time=2014-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=10623, encodeId=1d91106230c, content=关键如何应用于临床, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=123.150.123.159, createdTime=Fri Jul 25 20:33:00 CST 2014, time=2014-07-25, status=1, ipAttribution=)]
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    2014-07-25 123.150.123.159

    关键如何应用于临床

    0

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