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吴永健:介入治疗糖尿病伴复杂冠脉病变患者,2年后生活质量与搭桥手术不相上下

2018-08-26 朱柳媛 中国循环杂志

阜外医院吴永健研究团队发现,对于糖尿病合并冠心病复杂病变的患者来说,接受心脏搭桥术或冠脉介入治疗,随访2年时的健康状况或生活质量没什么差别。

阜外医院吴永健研究团队发现,对于糖尿病合并冠心病复杂病变的患者来说,接受心脏搭桥术或冠脉介入治疗,随访2年时的健康状况或生活质量没什么差别。

该研究选取在阜外医院行心脏搭桥术的757 例(CABG 组)及介入治疗手术的3 068例(PCI组)的2 型糖尿病合并稳定性冠心病患者,对其中复杂病变(SYNTAX 评分≥ 33 分)的178 例患者进行了西雅图心绞痛问卷的随访调查,以分析两种血运重建策略对术后功能和情绪健康状态的影响。

平均随访时间约为2 年,结果显示,CABG 组和PCI 组间的健康状况或生活质量没有差异。

CABG 组的89.7%和PCI 组90.3%的患者在日常活动时没有限制或只有轻微限制。CABG 组81.9%的患者和PCI组的79.0%患者其日常生活中没有或仅有轻微心绞痛发作。CABG 组88.8%的患者的反应是“对生活质量基本满意或多数情况满意”,在PCI 组中这一反应占87.1%。

该研究团队还发现,糖尿病病程是介入治疗术后生活质量评分降低的独立危险因素(HR=1.08,95% CI: 1.03~1.14,P=0.003),慢性阻塞性肺疾病史(HR=3.78,95% CI: 2.31~6.17,P<0.001)和高血压(HR=1.77,95% CI: 1.19~2.64,P=0.005)是心脏搭桥术后生活质量评分降低的独立危险因素。

原始出处:

侯晓沛,诸葛瑞琪,田艳蒙,等. 两种不同血运重建策略对2 型糖尿病合并稳定性冠心病复杂病变患者健康状况的影响. 中国循环杂志, 2018, 33: 631-636.

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    2018-08-27 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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    2018-08-26 131****2916

    不错的文章值得推荐一下

    0

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    2018-08-26 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2018-08-26 huangshang9812

    嗯,感觉靠谱

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