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血中抓“凶” 细菌哪里逃?

2018-07-04 李丁 检验医学网

看到下面的图片,不知您想到什么?药水?饮料?试剂?它其实是微生物培养常用的血培养,顾名思义,就是把患者血液进行培养检测,看看有没有引起疾病的“凶手”——可疑感染的病原菌,以便更准确的用药治疗。血培养呢,说简单也简单,就是抽血放入瓶子中由仪器培养细菌;说复杂也复杂,由于血培养一次用血量多(20-40ml),培养时间长,因此最理想的当然是用最少的血、最快的速度检出病原菌。要想事半功倍,当然需要有“小窍


作者:天津医科大学肿瘤医院检验科  李丁

看到下面的图片,不知您想到什么?药水?饮料?试剂?它其实是微生物培养常用的血培养,顾名思义,就是把患者血液进行培养检测,看看有没有引起疾病的“凶手”——可疑感染的病原菌,以便更准确的用药治疗。血培养呢,说简单也简单,就是抽血放入瓶子中由仪器培养细菌;说复杂也复杂,由于血培养一次用血量多(20-40ml),培养时间长,因此最理想的当然是用最少的血、最快的速度检出病原菌。要想事半功倍,当然需要有“小窍门”——那就是要在最佳的时间抽取血液送检。什么是最佳的时间呢?下面听小编娓娓道来:

1

当然是感染症状最为明显的时刻,感染表征离不开“红、肿、热、痛”,而发热是血流感染最普遍的症状,因此,出现发热,尤其是大于38℃的高热,是送检血培养的指征,但抽血的时刻应选择在患者体温上升期,也就是出现发冷、寒颤时,因为这时血液中的微生物正处于活跃状态,如果体温已经上升到峰值,过高的温度对微生物是一种抑制,再抽血反而不能得到良好的结果。

2

但仅仅发热是感染的表征吗?当然没有这么简单,有时重症感染体温不升反降,因此,如果患者体温小于36℃也是送检血培养的良好时机。

3

此外,感染还会造成低血压,皮肤黏膜瘀斑,儿童和老人可能会出现神经系统症状,如谵妄、昏迷等,这时都应该高度怀疑血流感染的存在,应及时送检血培养。

4

虽然血培养是诊断“血流感染”的金标准,但绝不是仅在怀疑血流感染时才需要送检血培养,因为人体中每一处微小的部位都有血液的滋养,身体脏器甚至表皮感染的微生物都可能入血,产生菌血症,血培养结果可以反映身体脏器尤其是血流丰富脏器的感染情况,因此,在出现肺部感染、尿路感染、脑膜炎等情况时,感染部位的标本不易留取如脑脊液,或痰、尿等标本易受定植菌污染,不能反映真实的感染症状,这是就需要血培养来帮忙,抓出元凶,找到真正的致病菌,帮助临床制定治疗策略。

5

最后,对于中性粒细胞缺乏(多数可能是血液病患者,或长期放化疗患者)、免疫功能低下患者,即使没有明显的感染症状也应定期检测血培养,因为这类患者极易感染,且预后极差,出现感染症状后再送检血培养可能就错过了治疗的最佳时机。

当您掌握了血培养送检最佳时间的小窍门,就能为临床医生诊断提供有效依据,为感染性疾病的治疗保驾护航。

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    2018-07-20 1771ae4158m

    学习一下很不错

    0

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    2018-07-11 1771ae4158m

    学习一下.很不错

    0

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    2018-07-08 txqjm

    谢谢了.学习

    0

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    2018-07-07 1771ae4158m

    学习一下很不错

    0

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    2018-07-05 哈哈869

    学了

    0

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    2018-07-05 哈哈869

    学了

    0

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    2018-07-05 魏医生

    小细胞肺癌

    0

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    2018-07-05 zb1235672

    学习了!!!

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    2018-07-05 yjs木玉

    学习学习再学习

    0

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    2018-07-05 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0

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