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Int J Implant Dent:猪胶原蛋白基质可有效替代自体软组织进行角化龈增宽

2018-02-04 MedSci MedSci原创

当牙种植体周围的角化龈宽度不足时,临床医生可以采用自体软组织移植。但是,自体软组织移植手术通常伴有一定程度的并发症。胶原基质可以用作减少并发症和手术时间的替代方法。本研究旨在评估异种胶原基质作为牙种植体周围软组织移植的替代物的功效。研究共纳入了15名种植术中植体接受前庭成形术和角化组织重建的患者,手术材料为猪胶原蛋白基质。术后6个月、1年、4年和5年后测量和评估所获得的角化组织。结果显示,术后角化

当牙种植体周围的角化龈宽度不足时,临床医生可以采用自体软组织移植。但是,自体软组织移植手术通常伴有一定程度的并发症。胶原基质可以用作减少并发症和手术时间的替代方法。本研究旨在评估异种胶原基质作为牙种植体周围软组织移植的替代物的功效。

研究共纳入了15名种植术中植体接受前庭成形术和角化组织重建的患者,手术材料为猪胶原蛋白基质。术后6个月、1年、4年和5年后测量和评估所获得的角化组织。

结果显示,术后角化组织的平均增加了5.7mm。6个月后,角化组织吸收37%,1年后48%,5年后59%。5年后角化组织的平均增长为2.4mm。同时,研究人员还评估了手术的止血效果和术后疼痛。所有受试者都提到了微小疼痛,无出血,没有发生不良反应和感染

综上所述,该研究结果肯定了软组织增量中使用猪胶原基质的效果。单一手术治疗中使用软组织替代品治疗可降低自体组织移植的许多并发症,还可提供大面积的软组织需求,因而具有较大的应用前景。

原始出处:

C. Maiorana, L. Pivetti, et al., The efficacy of a porcine collagen matrix in keratinized tissue augmentation: a 5-year follow-up study. Int J Implant Dent. 2018 Dec; 4: 1. doi:  10.1186/s40729-017-0113-3

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    2018-02-06 xuyong536
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    2018-04-06 xuyu
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    2018-02-06 qilu_qi
  5. [GetPortalCommentsPageByObjectIdResponse(id=1757077, encodeId=e9a11e570772e, content=<a href='/topic/show?id=103b421e0e8' target=_blank style='color:#2F92EE;'>#基质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42170, encryptionId=103b421e0e8, topicName=基质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=281337296540, createdName=ms7899726347904398, createdTime=Sun Feb 18 01:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773198, encodeId=deca1e7319899, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Tue Feb 06 19:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789170, encodeId=3bce1e89170e6, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Apr 06 01:48:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420405, encodeId=afdd142040583, content=<a href='/topic/show?id=2221935219e' target=_blank style='color:#2F92EE;'>#软组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93521, encryptionId=2221935219e, topicName=软组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52913579937, createdName=qilu_qi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485576, encodeId=925d14855e688, content=<a href='/topic/show?id=26aa9092296' target=_blank style='color:#2F92EE;'>#角化龈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90922, encryptionId=26aa9092296, topicName=角化龈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7c68007943, createdName=ms1779634646866130, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485702, encodeId=39121485e026d, content=<a href='/topic/show?id=8f0c840392a' target=_blank style='color:#2F92EE;'>#胶原蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84039, encryptionId=8f0c840392a, topicName=胶原蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11fc8038511, createdName=12498e5fm14(暂无昵称), createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555271, encodeId=6edf15552e12f, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1757077, encodeId=e9a11e570772e, content=<a href='/topic/show?id=103b421e0e8' target=_blank style='color:#2F92EE;'>#基质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42170, encryptionId=103b421e0e8, topicName=基质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=281337296540, createdName=ms7899726347904398, createdTime=Sun Feb 18 01:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773198, encodeId=deca1e7319899, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Tue Feb 06 19:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789170, encodeId=3bce1e89170e6, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Apr 06 01:48:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420405, encodeId=afdd142040583, content=<a href='/topic/show?id=2221935219e' target=_blank style='color:#2F92EE;'>#软组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93521, encryptionId=2221935219e, topicName=软组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52913579937, createdName=qilu_qi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485576, encodeId=925d14855e688, content=<a href='/topic/show?id=26aa9092296' target=_blank style='color:#2F92EE;'>#角化龈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90922, encryptionId=26aa9092296, topicName=角化龈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7c68007943, createdName=ms1779634646866130, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485702, encodeId=39121485e026d, content=<a href='/topic/show?id=8f0c840392a' target=_blank style='color:#2F92EE;'>#胶原蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84039, encryptionId=8f0c840392a, topicName=胶原蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11fc8038511, createdName=12498e5fm14(暂无昵称), createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555271, encodeId=6edf15552e12f, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1757077, encodeId=e9a11e570772e, content=<a href='/topic/show?id=103b421e0e8' target=_blank style='color:#2F92EE;'>#基质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42170, encryptionId=103b421e0e8, topicName=基质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=281337296540, createdName=ms7899726347904398, createdTime=Sun Feb 18 01:48:00 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773198, encodeId=deca1e7319899, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Tue Feb 06 19:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789170, encodeId=3bce1e89170e6, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Apr 06 01:48:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1420405, encodeId=afdd142040583, content=<a href='/topic/show?id=2221935219e' target=_blank style='color:#2F92EE;'>#软组织#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93521, encryptionId=2221935219e, topicName=软组织)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=52913579937, createdName=qilu_qi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485576, encodeId=925d14855e688, content=<a href='/topic/show?id=26aa9092296' target=_blank style='color:#2F92EE;'>#角化龈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90922, encryptionId=26aa9092296, topicName=角化龈)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7c68007943, createdName=ms1779634646866130, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1485702, encodeId=39121485e026d, content=<a href='/topic/show?id=8f0c840392a' target=_blank style='color:#2F92EE;'>#胶原蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84039, encryptionId=8f0c840392a, topicName=胶原蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11fc8038511, createdName=12498e5fm14(暂无昵称), createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555271, encodeId=6edf15552e12f, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Tue Feb 06 04:48:00 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-06 muzishouyi
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