做一次八九千的PET/CT有啥优势

2018-03-16 周鑫北京世纪坛医院宣传中心

很多人不知道PET/CT是什么，也分不清楚CT、MRI的区别是什么，更不清楚PET/CT在肿瘤诊断上的优势，今天给大家简单的聊聊这些相关的小知识

从原理上讲：

PET/CT是将放射性的药物（FDG，即葡萄糖类似物）静脉注入被检者的体内，经血液循环运送至全身，并通过细胞表面的葡萄糖转运受体（GLUT）被细胞吸收，然后放射性药物发射射线，通过机器采集射线信息，从而反映放射性药物的分布，功能越活跃，摄取FDG越多，在图像上则越浓；利用低剂量CT进行解剖定位，实现功能显像与解剖定位的有机结合。肿瘤细胞代谢活跃，能吸收更多的FDG，在影像上表现为放射性浓聚影，肿瘤组织功能改变可能较形态改变早，因此PET/CT检查能实现肿瘤的早期筛查。

CT则是利用设备发射X线，穿过被检者的组织结构时发生吸收衰减，由探测器接收衰减后的射线并转换成电信号，再经模拟/数字转换成数字化影像。由于人体各组织器官密度的不同，在探测器上形成不同密度的组织影。

MRI，也就是大家常说的磁共振，是对某种磁场中的人体施加特定的射频脉冲，与人体内的氢质子产生共振，停止发射脉冲后，氢质子产生信号，被接收线圈接收，再利用梯度磁场进行空间定位，最后进行图像重建形成可见的影像学图像。

那么PET/CT对于肿瘤诊断的优势有哪些呢？

（1）PET/CT对肿瘤的早期诊断具有很大的优势。人类的很多疾病在早期会先出现功能上的异常，PET提供病灶详尽的功能与代谢等分子信息，具有灵敏、准确、特异及定位精确等特点。此时进行PET/CT检查，一次显像可获得全身各方位的断层图像，了解全身整体状况，达到早期发现病灶、诊断疾病和治疗疾病的目的。CT和MRI则是病变导致解剖结构发生改变时才能明确病灶，且两者均为局部显像，CT的诊断剂量较高。若患者体内装有支架，起搏器等金属部件，是MRI检查的禁忌，行CT检查时会产生伪影，影像诊断。

（2）PET/CT为全身显像，恶性肿瘤通常伴其他部位的转移，PET/CT能更全面观察全身转移病灶的情况，帮助肿瘤分期及临床决策。

（3）PET/CT对于监测治疗效果及监测肿瘤复发有明显优势。以淋巴瘤患者为例，化疗后，患者的病灶大小可能没有发生变化，但病灶的代谢活性已明显减低，PET/CT评估提示化疗有效，而普通影像学检查可能无法给出结论；另外对于肿瘤患者，治疗后最常面临的问题就是肿瘤复发，PET/CT可以在形态学发生改变前即发现转移病灶，较普通影像学更早，且更全面；对于消化道肿瘤患者，PET/CT较其他影像学检查能更好地检测是否发生肝转移，且检出率高。

（4）对于不明原因发热患者，PET/CT可以帮助寻找病因；PET/CT作为一种新的影像检查技术，较X线、CT、MRI等传统影像学检查方法在不明原因发热患者的诊断中敏感性更高，能尽早明确病因，作出诊断，缩短治疗时间，降低治疗成本。

最后划重点：PET/CT在肿瘤的早期筛查诊断、观察病灶转移、监测疗效、查找发热病因等方面具有优势。

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2019-01-26 feather89

#PE#

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2018-03-18 易水河

学习了.PET/CT在肿瘤的早期筛查诊断.观察病灶转移.监测疗效.查找发热病因等方面具有优势

100 0
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createdTime=Sat Mar 17 22:06:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297141, encodeId=ad8729e141e3, content=PET/CT可以在形态学发生改变前即发现转移病灶.较普通影像学更早.且更全面,对于消化道肿瘤患者.PET/CT较其他影像学检查能更好地检测是否发生肝转移.且检出率高., beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sat Mar 17 16:45:14 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296810, encodeId=959429681065, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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2018-03-18 chaojitidian

#PET/CT#

77 0
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2018-03-18 ms7514935887898259

#PET#

78 0
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2018-03-17 sunfeifeiyang

阅

101 0
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createdTime=Sat Mar 17 22:06:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297141, encodeId=ad8729e141e3, content=PET/CT可以在形态学发生改变前即发现转移病灶.较普通影像学更早.且更全面,对于消化道肿瘤患者.PET/CT较其他影像学检查能更好地检测是否发生肝转移.且检出率高., beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sat Mar 17 16:45:14 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296810, encodeId=959429681065, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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2018-03-17 sunfeifeiyang

阅

97 0
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2018-03-17 神功盖世

阅

90 0
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2018-03-17 沙漠浪人

PET/CT可以在形态学发生改变前即发现转移病灶.较普通影像学更早.且更全面,对于消化道肿瘤患者.PET/CT较其他影像学检查能更好地检测是否发生肝转移.且检出率高.

85 0
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2018-03-16 戒馋，懒，贪

谢谢分享学习了

0 0
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2018-03-16 神功盖世

阅

55 0