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Am J Epidemiol:中国慢病前瞻性研究,2型糖尿病患者肝癌、胰腺癌和乳腺癌罹患风险高

2018-01-17 卢芳 中国循环杂志

糖尿病的危害不止伤血管,近期来自中国慢病前瞻性研究的一项对50余万人平均随访7.1年的最新研究结果显示,2型糖尿病会增加癌症风险,特别是肝癌、胰腺癌和乳腺癌的风险。


糖尿病的危害不止伤血管,近期来自中国慢病前瞻性研究的一项对50余万人平均随访7.1年的最新研究结果显示,2型糖尿病会增加癌症风险,特别是肝癌、胰腺癌乳腺癌的风险。
 
研究显示,2型糖尿病患者的总体癌症风险增加13%,此外肝癌、胰腺癌和女性乳腺癌风险分别增加51%、86%和21%。
 
而且,在既往未诊断的2型糖尿病人群中,较高的随机血糖水平也与总体癌症、肝癌和女性乳腺癌风险呈正性关系。
 
研究者指出,鉴于2型糖尿病和癌症的疾病负担,对2型糖尿病患者密切监测其早发癌症,或有助于预防癌症,不过这种筛查费用和效果仍需大样本临床试验来支持。
 
这项中国前瞻性慢性病研究最新分析,共于2004-2008年纳入508892位基线无癌症的受试者,其中有29835人罹患糖尿病,平均年龄为51.5岁。随访至2013-12-31时,共有17 463人罹患癌症。
 
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