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Clin Implant Dent Relat Res:使用脱蛋白猪与脱矿牛骨在骨缺损拔牙窝中的牙槽嵴再生

2018-08-04 MedSci MedSci原创

目前已知完整拔牙窝行骨移植的临床益处,但是对于牙周病导致骨缺损的拔牙窝行骨移植的益处知之甚少。本研究旨在确定受损拔牙窝移植后牙槽嵴的尺寸变化,并比较在受损窝中使用脱蛋白牛(DBBM)与猪骨矿物质(DPBM)的结果。这项随机单盲试验纳入了100名患有牙周炎诱导的受损拔牙窝的患者(每组n = 50)。拔除牙齿,去净肉芽组织后,用DBBM(DBBM组)或DPBM(DPBM组)移植部位,并用胶原膜覆盖。在

目前已知完整拔牙窝行骨移植的临床益处,但是对于牙周病导致骨缺损的拔牙窝行骨移植的益处知之甚少。本研究旨在确定受损拔牙窝移植后牙槽嵴的尺寸变化,并比较在受损窝中使用脱蛋白牛(DBBM)与猪骨矿物质(DPBM)的结果。

这项随机单盲试验纳入了100名患有牙周炎诱导的受损拔牙窝的患者(每组n = 50)。拔除牙齿,去净肉芽组织后,用DBBM(DBBM组)或DPBM(DPBM组)移植部位,并用胶原膜覆盖。在重建/叠加的计算机断层扫描和扫描的铸造图像上进行硬组织和软组织尺寸的线性/体积分析,分别在术后即刻和手术后4个月进行。

结果显示,手术后4个月,两组硬组织增量结果相当,移植组织较少较小,垂直方向(DPBM和DBBM组分别为1.22±2.16和1.45±1.92 mm)和水平方向(DPBM和DBBM组分别为1.43±3.40和1.83±2.85 mm)。但是,有几个病例表明移植体积的维持存在很大差异。在DBBM和DPBM位点之间,硬组织和软组织尺寸测量参数都没有明显差异。

综上所述,该研究结果表明,骨缺损拔牙窝植入DBBM和DPBM都可达到骨增量的目的,同时术后移植体积减少最小。但是,应进一步评估该结果,以便在牙科诊所中应用。

原始出处:

Lee JS, Cha JK, Kim CS. Alveolar ridge regeneration of damaged extraction sockets using deproteinized porcine versus bovine bone minerals: A randomized clinical trial. Clin Implant Dent Relat Res. 2018 Jul 27. doi: 10.1111/cid.12628.

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    2018-10-12 kksonne
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    2019-06-21 xuyu
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    2018-12-17 xuyong536
  5. [GetPortalCommentsPageByObjectIdResponse(id=2016352, encodeId=c2f4201635251, content=<a href='/topic/show?id=01336e58417' target=_blank style='color:#2F92EE;'>#牙槽嵴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67584, encryptionId=01336e58417, topicName=牙槽嵴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Fri Oct 12 03:21:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994439, encodeId=58d7199443966, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Wed Dec 05 17:21:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789186, encodeId=b7de1e8918670, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Jun 21 09:21:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773210, encodeId=57a51e732100f, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Mon Dec 17 01:21:00 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419268, encodeId=a2c31419268e2, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555282, encodeId=27c815552828b, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574230, encodeId=8bd715e423008, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336369, encodeId=308c33636982, content=学习了!谢谢作者的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151002/IMG560DED22850969184.jpg, createdBy=6c9b1653645, createdName=王小白0816, createdTime=Sat Aug 04 14:48:13 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-06 lfcmxl
  6. [GetPortalCommentsPageByObjectIdResponse(id=2016352, encodeId=c2f4201635251, content=<a href='/topic/show?id=01336e58417' target=_blank style='color:#2F92EE;'>#牙槽嵴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67584, encryptionId=01336e58417, topicName=牙槽嵴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Fri Oct 12 03:21:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994439, encodeId=58d7199443966, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Wed Dec 05 17:21:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789186, encodeId=b7de1e8918670, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Jun 21 09:21:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773210, encodeId=57a51e732100f, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Mon Dec 17 01:21:00 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419268, encodeId=a2c31419268e2, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555282, encodeId=27c815552828b, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574230, encodeId=8bd715e423008, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336369, encodeId=308c33636982, content=学习了!谢谢作者的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151002/IMG560DED22850969184.jpg, createdBy=6c9b1653645, createdName=王小白0816, createdTime=Sat Aug 04 14:48:13 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-06 muzishouyi
  7. [GetPortalCommentsPageByObjectIdResponse(id=2016352, encodeId=c2f4201635251, content=<a href='/topic/show?id=01336e58417' target=_blank style='color:#2F92EE;'>#牙槽嵴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67584, encryptionId=01336e58417, topicName=牙槽嵴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Fri Oct 12 03:21:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994439, encodeId=58d7199443966, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Wed Dec 05 17:21:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789186, encodeId=b7de1e8918670, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Jun 21 09:21:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773210, encodeId=57a51e732100f, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Mon Dec 17 01:21:00 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419268, encodeId=a2c31419268e2, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555282, encodeId=27c815552828b, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574230, encodeId=8bd715e423008, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336369, encodeId=308c33636982, content=学习了!谢谢作者的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151002/IMG560DED22850969184.jpg, createdBy=6c9b1653645, createdName=王小白0816, createdTime=Sat Aug 04 14:48:13 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-06 xre2013
  8. [GetPortalCommentsPageByObjectIdResponse(id=2016352, encodeId=c2f4201635251, content=<a href='/topic/show?id=01336e58417' target=_blank style='color:#2F92EE;'>#牙槽嵴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67584, encryptionId=01336e58417, topicName=牙槽嵴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Fri Oct 12 03:21:00 CST 2018, time=2018-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1994439, encodeId=58d7199443966, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Wed Dec 05 17:21:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789186, encodeId=b7de1e8918670, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Jun 21 09:21:00 CST 2019, time=2019-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1773210, encodeId=57a51e732100f, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Mon Dec 17 01:21:00 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419268, encodeId=a2c31419268e2, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555282, encodeId=27c815552828b, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574230, encodeId=8bd715e423008, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Mon Aug 06 05:21:00 CST 2018, time=2018-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336369, encodeId=308c33636982, content=学习了!谢谢作者的分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151002/IMG560DED22850969184.jpg, createdBy=6c9b1653645, createdName=王小白0816, createdTime=Sat Aug 04 14:48:13 CST 2018, time=2018-08-04, status=1, ipAttribution=)]
    2018-08-04 王小白0816

    学习了!谢谢作者的分享!

    0

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