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J Periodontol:牙周炎伴随偏头痛患者血清中的高原降钙素水平研究

2018-03-18 lishiting MedSci原创

这篇横向研究的目的是为了评估慢性牙周炎(CP)对慢性偏头疼(CM)患者血清原降钙素(proCT)水平的影响。

这篇横向研究的目的是为了评估慢性牙周炎(CP)对慢性偏头疼(CM)患者血清原降钙素(proCT)水平的影响。

研究将138名受试者按照CM的临床特征和牙周指标分为4组:全身和牙周健康的个体(n = 37),全身健康的CP患者(n = 19),CM但牙周健康的患者(n = 34)和CM+CP患者(n = 48)。获取各组的人数、神经和临床数据以及全口牙周记录。在偏头疼发作期间,抽取患者血液样本,检测其血清中的ProCT和高敏感C反应蛋白(hs-CRP)水平。

结果显示,与全身和牙周健康组(0.029±0.019 ng/mL), CM组(0.041±0.002 ng/mL)或CP组(0.034±0.014 ng/mL)相比,CP+CM组患者的血清proCT水平更高(0.056±0.006 ng/mL) (p < 0.001)。各组间hs-CRP水平未见明显差异(p = 0.081)。多次线性回归分析显示,CP与CM患者的proCT水平相关联(R2 = 0.293, p < 0.001)。

结论:CP会单独影响CM患者血清proCT水平的上升。这些结果表明,CP对慢性偏头疼具有一定的影响。

原始出处

Leira Y, Ameijeira P, et al. High serum procalcitonin levels in patients with periodontitis and chronic migraine. J Periodontol. 2018 Mar 9. doi: 10.1002/JPER.17-0603.

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    2018-05-23 feather89
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    2018-03-20 jmtang
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    2018-03-18 戒馋,懒,贪

    谢谢分享学习了

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