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噬肉菌究竟是什么鬼?四天杀死一男子!

2018-04-01 小闪 检验医学网

Marcia Funk回忆说,这就像是恐怖电影里发生的故事。她的丈夫Michael Funk在短短四天内死于致命噬肉菌。Michael是在清理蟹笼时腿上的小伤口感染了致命的创伤弧菌(Vibrio vulnificus)。数小时内,他就病倒了,送去了附近的医院,医生动手术切割了感染处,但噬肉菌已经进入了血液。他的情况快速恶化,很快去世。


Marcia Funk回忆说,这就像是恐怖电影里发生的故事。她的丈夫Michael Funk在短短四天内死于致命噬肉菌。Michael是在清理蟹笼时腿上的小伤口感染了致命的创伤弧菌(Vibrio vulnificus)。数小时内,他就病倒了,送去了附近的医院,医生动手术切割了感染处,但噬肉菌已经进入了血液。他的情况快速恶化,很快去世。

过去四十年,感染和死于创伤弧菌的人数在持续增加。全球暖化被认为是原因之一。温暖的海表水导致了创伤弧菌数量激增,因此而引起了感染病例的增加。

以下图片可能会引起不适,非医学专业人士回避!



其他案例

年轻男子嘴唇四肢被噬肉菌蚀掉

34岁的亚历克斯·刘易斯患普通感冒,但随后感染了乙型溶血性链球菌A,引起了败血病和中毒性休克综合征,导致器官衰竭和一周昏迷。

这场普通感冒恶化成的致命病毒——食肉菌吞噬了他的手臂、双腿和面部。他只能将已变黑的两条腿和一条手臂截肢。

在救治过程中,他还失去了嘴唇和部分鼻子,但在长达20个小时的手术之后,医生最终用他肩上的皮肤和肉为他重塑了嘴唇。

为了使其嘴唇有足够供血而重现血色,外科医生亚历山大·克里克打开了他的嘴巴并且缝了一个临时海绵泡,将其两条血管和动脉接合在了一起,嘴唇边缘皮肤将最终收缩并与面部皮肤同色。

如果恢复过程一切正常,他嘴唇左侧缝上的其它皮肤将在两周后褪去,而嘴唇周边的新皮肤将最终收缩,与面部皮肤同色而不留伤疤。



美少年左腿感染罕见噬肉菌 无奈截肢保命

《每日邮报》8月20日报道,近日,美国密歇根州底特律市的12岁男孩小达卡莱?摩尔(Dakarai Moore Jr.)因罕见细菌侵入腿部,迅速破坏了皮肤、脂肪以及筋膜中的组织,其父母沙法尔?诺曼(Charmaine Norman)和达卡?摩尔(Dakarai Moore)不得不忍痛决定截掉其左腿以保其性命。



据悉,小摩尔在8月10日运动时突觉膝盖肿胀,小腿紧绷。没过几日,因腿部剧烈疼痛入院检查。此后他身体情况迅速恶化,最终医生确证他患上了坏死性筋膜炎,一种21岁以上的成年人更易染上的疾病。细菌在他腿部扩散,他的双腿均已受感染,幸而医生控制住了右腿细菌的扩散。可惜的是,小摩尔左腿因感染严重,不得不通过截肢保命。小摩尔的父母为此痛心不已,不过他们呼吁更多的人能够了解这种疾病。

噬肉菌是什么鬼?

噬肉菌,又称为食肉菌,食肉菌并非单一细菌,而是指由不同细菌引发的坏死性筋膜炎,是对于链球菌或者能造成肌肉组织损坏的菌类总称。食肉菌(flesh-eating bacteria)亦非靠食肉繁殖,主要透过伤口入侵皮下筋膜,在感染阶段向感染者释放毒素破坏患者的表皮和肌肉组织,该毒素会触发T淋巴细胞的防御机制,因此也会导致患者的局部组织细胞增生。

早在公元前5世纪,希腊名医希波克拉底已曾描述食肉菌的症状,令食肉菌首次走进人类文献。1884年,法国病理学大师巴斯德(LouisPasteur)再进一步发现一名女性身上出现食肉菌的踪迹,成为现代同类文献的先驱。

不过,在过去百年,即使该病菌毒性剧烈,但因较为罕见,一直没有引起外界注意。直到1990年代中后期,媒体为该菌冠上“食肉菌”(flesh-eating bacteria)“恶名”后,此菌才备受关注。
 
临床病症

食肉菌早期的病征和流感相似,包括发热、肌肉酸痛、咽喉疼痛等等。跟着,患者皮肤的伤口会越来越痛,体温会越来越高,肌肉和身体组织开始受到破坏。血压可能下降,影响血液循环,进一步使身体组织坏死。症状可能为表皮可见,也可能发生在患者真皮层而表皮完好,感染部位发红肿胀,伴有出血和皮质变硬,后期产生腹泻和发烧等并发症状。最常见的有化脓链球菌和创伤弧菌。

细菌会在任何筋膜部位感染,病人必须尽快入院切除坏死组织并处方抗生素,否则可致败血病及多种器官衰竭,数小时内可致命。

主要危害 

食肉菌的可怕之处就是毒性太强,抵抗力差的人根本无法抵御。它在人不经意时就袭击到人的体内,可能是你在花园里割草时不小心划破伤口的时候,也可能是在你洗虾子,被虾钳戳了一下手的时候,甚至是被一些微小昆虫叮咬,食肉菌都可以从这些小小的伤口进入人体吞噬着生命。

此外,人感染“食肉菌”,未必就会出现严重病发。患者的皮肤及脂肪可能只会出现所谓“蜂组织炎”,病情一般较轻,但若病情拖延,病人可患上“坏死性筋膜炎”。病人患病的严重程度,往往取决于个人体质,若本身免疫力较差,譬如有肝脏问题或糖尿病,易出现比较严重的感染。

传播途径

噬肉菌非常容易在海鲜上出现,涉及弧菌性的个案多与海产品有关。垂钓、潜水或是在街市买海产被海鲜弄伤了手,都有机会感染食肉菌,但在众多感染途径中,吃生蚝风险最高。如果不小心被买回来的海鲜弄伤了手,记住,要马上用消毒药水清洁,不可随意处理,这种病菌会侵蚀你的肌肉,严重的话可能会在24小时之内将你致命。

治疗方法

使用抗生素治疗。动手术切除坏死的身体组织。在痊愈后用物理治疗帮助患者的肌肉恢复力量

预防措施

香港大学感染及传染病中心专家指出,食肉菌可由不同的细菌引致,最常见的是甲类链球菌,创伤弧菌也可以引致坏死性筋膜炎。

创伤弧菌通常存在于温暖的海水中。环境性因素,如温暖的海水,能增加贝壳类海产(如蚝、蚬及青口等)内创伤弧菌的数目,但很少引起人类皮肤发炎感染。不过,免疫力低下的人,如糖尿病患者、慢性肾病患者及肝病患者等则要小心,若被这些海产刺伤皮肤,致病菌可从伤口入侵。

 所以,如在处理海鲜时弄伤手,应即时以清水冲洗伤口。如出现受感染的病征,如皮肤红肿、疼痛、发热等,应立即求医。最有效预防防方法是妥善消毒及包扎伤口, 如果出现上述症状,必须马上求医,不可拖延。

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    2018-04-03 wzb521zf

    一起学习学习

    0

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    2018-04-03 changjiu

    学习一下谢谢

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    2018-04-02 lou.minghong

    恐怖的微生物!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=302284, encodeId=87c130228482, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Tue Apr 03 06:37:41 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302222, encodeId=7402302222e2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Tue Apr 03 03:01:20 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301966, encodeId=065530196666, content=恐怖的微生物!, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Mon Apr 02 07:20:58 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301950, encodeId=af5630195069, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Apr 02 06:56:49 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301872, encodeId=fdd73018e284, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Apr 02 00:19:33 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301842, encodeId=36a03018424a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Apr 01 23:31:10 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-04-02 飛歌

    学习了很有用

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=302284, encodeId=87c130228482, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=150, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Tue Apr 03 06:37:41 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=302222, encodeId=7402302222e2, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=145, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Tue Apr 03 03:01:20 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301966, encodeId=065530196666, content=恐怖的微生物!, beContent=null, objectType=article, channel=null, level=null, likeNumber=2, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Mon Apr 02 07:20:58 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301950, encodeId=af5630195069, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Mon Apr 02 06:56:49 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301872, encodeId=fdd73018e284, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Mon Apr 02 00:19:33 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301842, encodeId=36a03018424a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sun Apr 01 23:31:10 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-04-02 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-04-01 秀红

    学习了

    0

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