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Biomater. Sci:人造纤维可“清理”血液尿毒症毒素

2014-02-20 佚名 新华网

日本物质和材料研究机构日前发表一份公报称,其研究人员开发出一种人造纤维,能够吸附肾衰竭患者血液中所含的尿毒症毒素肌酐,这一成果将有助于开发便携式小型透析装置。 该机构主任研究员荏原充宏率领的研究小组,将能够吸附肌酐的沸石混合到树脂中,制作出了一种极细的纤维,并将这种纤维制成无纺布。血清实验显示,只要约16克纤维,就可以将体重60公斤的人在1小时之内产生的肌酐全部吸附干净。 肌酐是血液中的一种低

日本物质和材料研究机构日前发表一份公报称,其研究人员开发出一种人造纤维,能够吸附肾衰竭患者血液中所含的尿毒症毒素肌酐,这一成果将有助于开发便携式小型透析装置。【原文下载

该机构主任研究员荏原充宏率领的研究小组,将能够吸附肌酐的沸石混合到树脂中,制作出了一种极细的纤维,并将这种纤维制成无纺布。血清实验显示,只要约16克纤维,就可以将体重60公斤的人在1小时之内产生的肌酐全部吸附干净。

肌酐是血液中的一种低分子尿毒症毒素,由肌酸分解形成,是反映肾功能情况的主要指标。肾脏功能正常运作时,肌酐会经尿液排泄至体外,但肾衰竭患者的肾脏无法过滤干净血液中的代谢废物和尿毒症毒素,所以必须进行透析。

除了肌酐,尿毒症毒素还有很多种。研究小组认为,通过更换沸石的种类,可以制造出吸附其他尿毒症毒素的人造纤维。这一成果的论文已经刊登在新一期《生物材料科学》杂志上。

目前,仅日本国内就有30多万慢性肾衰竭患者接受透析治疗,每年需要耗费约200亿美元的医疗费。透析装置较大且费水费电,给患者造成很多不便。

原始出处

Koki Namekawa, Makoto Tokoro Schreiber, Takao Aoyagi and Mitsuhiro Ebara. Fabrication of zeolite–polymer composite nanofibers for removal of uremic toxins from kidney failure patients. Biomater. Sci., 31 Jan 2014; DOI: 10.1039/C3BM60263J
原文下载

原始链接

災害時に人工透析代替を目指す高性能ファイバーの開発

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    2015-01-25 sunylz
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    2014-02-22 tcm99hq
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