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Int J Implant Dent:种植体周围病部位龈沟液中钙卫蛋白和NTx水平的水平

2018-10-15 MedSci MedSci原创

种植体周围龈沟液(PICF)含有钙卫蛋白和NTx,分别是炎症和骨吸收的标志物。本研究旨在比较植入部位(有或没有种植体周围疾病)PICF中的钙卫蛋白和NTx水平,并评估钙卫蛋白和NTx作为种植体周围病诊断标志物的有效性。 研究纳入了35名牙种植体患者。临床指标包括探诊深度(PD)、探测出血(BOP)、牙龈指数(GI),从种植体周围病部位(n = 40)和健康部位(n = 34)收集PICF样本

种植体周围龈沟液(PICF)含有钙卫蛋白和NTx,分别是炎症和骨吸收的标志物。本研究旨在比较植入部位(有或没有种植体周围疾病)PICF中的钙卫蛋白和NTx水平,并评估钙卫蛋白和NTx作为种植体周围病诊断标志物的有效性。

研究纳入了35名牙种植体患者。临床指标包括探诊深度(PD)、探测出血(BOP)、牙龈指数(GI),从种植体周围病部位(n = 40)和健康部位(n = 34)收集PICF样本,并研究骨质丧失率(BL)。使用ELISA试剂盒测量PICF中的钙卫蛋白和NTx的水平,然后在患病和健康样品之间进行比较。研究了PICF钙卫蛋白或NTx水平与临床指标水平之间的关系。进行钙卫蛋白和NTx的受试者操作特征(ROC)曲线分析以预测种植体周围病。

结果显示,种植体周围疾病部位PICF中的钙卫蛋白和NTx水平明显高于健康部位。PICF钙卫蛋白的水平与PD相关,其在GI-1和GI-2组中的水平明显高于GI-0组。PICF NTx的水平与PD和BL率相关。ROC曲线表明PICF钙卫蛋白和NTx是种植体周围疾病的有用生物标志物。

原始出处:

Eijiro Sakamoto, Rie Kido, et al., Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases: a pilot study. Int J Implant Dent. 2018 Dec; 4: 26.

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    2018-12-21 xuyong536
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    2018-12-24 huangdf
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    2018-11-09 xuyu
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1773224, encodeId=fa1d1e732240f, content=<a href='/topic/show?id=5298121e46e' target=_blank style='color:#2F92EE;'>#MPL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12174, encryptionId=5298121e46e, topicName=MPL)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=10e638510530, createdName=xuyong536, createdTime=Fri Dec 21 20:09:00 CST 2018, time=2018-12-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1686891, encodeId=4fb2168689188, content=<a href='/topic/show?id=1fc71035e1c1' target=_blank style='color:#2F92EE;'>#龈沟液#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103571, encryptionId=1fc71035e1c1, topicName=龈沟液)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fa428300788, createdName=ms8435843352634314, createdTime=Wed May 01 09:09:00 CST 2019, time=2019-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1701991, encodeId=87f91e01991a6, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Mon Dec 24 13:09:00 CST 2018, time=2018-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1789200, encodeId=e9ef1e892007e, content=<a href='/topic/show?id=0c8814344f5' target=_blank style='color:#2F92EE;'>#plant#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14344, encryptionId=0c8814344f5, topicName=plant)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Fri Nov 09 07:09:00 CST 2018, time=2018-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343830, encodeId=015313438306a, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Wed Oct 17 13:09:00 CST 2018, time=2018-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=349459, encodeId=129134945916, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Mon Oct 15 22:14:41 CST 2018, time=2018-10-15, status=1, ipAttribution=)]
    2018-10-15 天地飞扬

    了解一下,谢谢分享!

    0

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