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EJEM:和肽素(copeptin)或可用作急性冠脉综合征的生物标记物

2013-09-18 佚名 生物谷

      科学家最近发现一种名为和肽素的物质可以作为急性冠脉综合症非常有效的生物标记物。通过和肽素监测,研究人员可以迅速确定患者是否为心脏病发作。一项有902人参与的临床研究显示,通过和肽素检测方法可以大大提高心脏病确诊的准确性。 一位英国的医生表示,在医院中有类似胸口疼痛等心脏病疑似症状的患者中大概只有10%真正患有急性心脏病。这一生物标记物如能应用,将大大提高医院工

  心脏

  

和肽素(copeptin)是近年来被认为是潜在的急性冠脉综合症非常有效的生物标记物。通过和肽素监测,研究人员可以迅速确定患者是否为心脏病发作。一项有902人参与的临床研究显示,通过和肽素检测方法可以大大提高心脏病确诊的准确性。其它相关研究也证实这一点。

一位英国的医生表示,在医院中有类似胸口疼痛等心脏病疑似症状的患者中大概只有10%真正患有急性心脏病。这一生物标记物如能应用,将大大提高医院工作效率。不过研究人员也承认,此方法距离实际应用还有一段距离。

原始出处:

Llorens P, Sánchez M, Herrero P, Martín-Sánchez FJ, Piñera P, Miró O; on behalf of COPED study investigators.The utility of copeptin in the emergency department for non-ST-elevation myocardial infarction rapid rule out: COPED-MIRRO study.Eur J Emerg Med. 2013 Jul 17.

Thelin J, Borna C, Erlinge D, Ohlin B.The combination of high sensitivity troponin T and copeptin facilitates early rule-out of ACS: a prospective observational study.BMC Cardiovasc Disord. 2013 Jun 18;13(1):42.

Afzali D, Erren M, Pavenstädt HJ, Vollert JO, Hertel S, Waltenberger J, Reinecke H, Lebiedz P.Impact of copeptin on diagnosis, risk stratification, and intermediate-term prognosis of acute coronary syndromes.Clin Res Cardiol. 2013 Oct;102(10):755-63.

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    2014-08-20 feather89
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    2014-07-07 wjywjy
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