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JID:不易晒黑+HPV抗体阳性,皮肤癌风险增加

2012-06-17 高晓方 翻译 中国医学论坛报

  紫外线照射及皮肤人乳头状瘤病毒(HPV)感染或对皮肤基底细胞癌(BCC)和鳞状细胞癌(SCC)的发生具协同交互作用。美国一项研究显示,对于α属或β属HPV血清抗体阳性者,若不易晒黑,则罹患皮肤SCC风险较高。论文于6月1日在线发表于《感染性疾病杂志》(J Infect Dis)。   研究纳入皮肤BCC患者204例,皮肤SCC患者156例,以及无肿瘤病史且当前皮肤癌筛查为阴性的对照297名。评

  紫外线照射及皮肤人乳头状瘤病毒(HPV)感染或对皮肤基底细胞癌(BCC)和鳞状细胞癌(SCC)的发生具协同交互作用。美国一项研究显示,对于α属或β属HPV血清抗体阳性者,若不易晒黑,则罹患皮肤SCC风险较高。论文于6月1日在线发表于《感染性疾病杂志》(J Infect Dis)。
  研究纳入皮肤BCC患者204例,皮肤SCC患者156例,以及无肿瘤病史且当前皮肤癌筛查为阴性的对照297名。评估日光暴露与皮肤BCC和SCC的相关性,并根据HPV血清学状况进行分层。
  结果为,皮肤对日光暴露敏感[易晒伤(P=0.006)及不易晒黑(P=0.003)]与β属HPV血清阳性率较高相关。与血清阴性者相比,对于α属[比值比(OR)为15.60]和β属(OR=6.86)HPV血清抗体阳性的个体,不易晒黑与SCC具有更强的相关性。


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    2012-06-27 sjq027
  2. [GetPortalCommentsPageByObjectIdResponse(id=2061326, encodeId=331720613263b, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Jun 27 06:22:00 CST 2012, time=2012-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2029741, encodeId=aae82029e4174, content=<a href='/topic/show?id=d7b510298e3' target=_blank style='color:#2F92EE;'>#JID#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10298, encryptionId=d7b510298e3, topicName=JID)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/UdV6ialcayj7Qv8RQm1mVfNYPKxjiaolxwglAZpCo6CwjTicOroW2Xb0Kxnc65viaxGpkuqHW7WzzbYgRLw3qooDoA/132, createdBy=04c22500137, createdName=紫砂壶, createdTime=Sun Sep 09 09:22:00 CST 2012, time=2012-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981009, encodeId=91ec198100952, content=<a href='/topic/show?id=3e3fe2073e5' target=_blank style='color:#2F92EE;'>#皮肤癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72073, encryptionId=3e3fe2073e5, topicName=皮肤癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sun Oct 21 01:22:00 CST 2012, time=2012-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1948088, encodeId=df73194808805, content=<a href='/topic/show?id=3aae55212db' target=_blank style='color:#2F92EE;'>#抗体阳性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55212, encryptionId=3aae55212db, topicName=抗体阳性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Sat Jun 01 00:22:00 CST 2013, time=2013-06-01, status=1, ipAttribution=)]
    2012-09-09 紫砂壶
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