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Respir Res:有趣的圣乔治呼吸问卷

2017-01-25 MedSci MedSci原创

目前尚不清楚健康相关的生活质量(HRQL)是否具有预测特发性肺纤维化(IPF)死亡率的价值。近期,一项发表在Respir Res杂志上的研究使用圣乔治呼吸问卷(SGRQ)评估HRQL与IPF患者的生存时间之间的关系,并尝试确定临床有意义的临界值以预测更差的存活率。此项研究回顾性分析了2007年5月至2012年12月接受初步评估的IPF患者。根据2011年国际共识指南进行IPF的诊断。研究者们使用C

目前尚不清楚健康相关的生活质量(HRQL)是否具有预测特发性肺纤维化(IPF)死亡率的价值。


近期,一项发表在Respir Res杂志上的研究使用圣乔治呼吸问卷(SGRQ)评估HRQL与IPF患者的生存时间之间的关系,并尝试确定临床有意义的临界值以预测更差的存活率。

此项研究回顾性分析了2007年5月至2012年12月接受初步评估的IPF患者。根据2011年国际共识指南进行IPF的诊断。研究者们使用Cox比例风险模型来确定IPF患者死亡率的独立预测因子。
研究共评估了182例符合条件的病例,平均年龄为66岁,86%为男性。预测FVC、DLCO、6分钟步行测试距离和SGRQ总分的平均水平分别为约80%、58%、580m和34分。在多变量分析中,SGRQ总分(风险比[HR],1.012;95%置信区间[CI],1.001-1.023;P=0.029)和预测FVC百分比(HR,0.957;95%CI,0.944-0.971,P<.001)是死亡率的独立预测因子。

此外,在SGRQ总分高于30分显示较高的死亡率(HR,2.047;95%CI,1.329-3.153;P=0.001)。

这项研究表明,SGRQ总分是IPF患者的独立预后因素之一。总分高于30分与较高的死亡率相关。

原始出处:
Furukawa T, Taniguchi H, Ando M, et al. The St. George's Respiratory Questionnaire as a prognostic factor in IPF. Respir Res. 2017 Jan 17;18(1):18. doi: 10.1186/s12931-017-0503-3.

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    2017-02-11 虈亣靌

    好文,值得点赞,值得拥有,值得收藏!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=175471, encodeId=80ec1e5471e4, content=好文,值得点赞,值得拥有,值得收藏!, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 11 04:30:01 CST 2017, time=2017-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174738, encodeId=f3e91e47384b, content=新进展,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Feb 07 13:19:55 CST 2017, time=2017-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=174173, encodeId=2cb71e41735e, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sat Feb 04 15:21:16 CST 2017, time=2017-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173411, encodeId=d5881e3411c9, content=(⊙o⊙), beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b592012715, createdName=1e1f3b8dm20(暂无匿称), createdTime=Tue Jan 31 08:28:04 CST 2017, time=2017-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=173287, encodeId=562a1e328772, content=SGRQ总分是IPF患者的独立预后因素之一。总分高于30分与较高的死亡率相关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Jan 30 10:26:28 CST 2017, time=2017-01-30, status=1, ipAttribution=)]
    2017-02-07 虈亣靌

    新进展,值得学习

    0

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    2017-02-04 doctorJiangchao

    继续学习

    0

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    2017-01-31 1e1f3b8dm20(暂无匿称)

    (⊙o⊙)

    0

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    2017-01-30 ylzr123

    SGRQ总分是IPF患者的独立预后因素之一。总分高于30分与较高的死亡率相关。

    0

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