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Allergy:武汉市140例SARS-CoV-2感染患者的临床特征

2020-02-23 不详 网络

严重急性呼吸系统综合症引起的冠状病毒病2019(COVID-19)冠状病毒-2(SARS-CoV-2)感染已广泛传播。我们旨在调查SARS-CoV-2感染患者的临床特征和过敏状况。提取并分析140例住院SAV-CoV-2病毒感染结果的电子病历,包括人口统计学,临床表现,合并症,实验室数据和放射学资料。结果显示,男性(50.7%)和女性COVID-19患者的比例约为1:1,总中位年龄为57.0岁。所

严重急性呼吸系统综合症引起的冠状病毒病2019(COVID-19)冠状病毒-2(SARS-CoV-2)感染已广泛传播。我们旨在调查SARS-CoV-2感染患者的临床特征和过敏状况。

提取并分析140例住院SAV-CoV-2病毒感染结果的电子病历,包括人口统计学,临床表现,合并症,实验室数据和放射学资料。

结果显示,男性(50.7%)和女性COVID-19患者的比例约为1:1,总中位年龄为57.0岁。所有患者均为社区获得性病例。发烧(91.7%),咳嗽(75.0%),疲劳(75.0%)和肠道症状(39.6%)是最常见的临床表现,而高血压(30.0%)和糖尿病(12.1%)是最常见的合并症。几位患者报告了药物超敏反应(11.4%)和荨麻疹(1.4%)。没有任何患者报告哮喘或其他过敏性疾病。慢性阻塞性肺疾病(COPD,1.4%)和当前吸烟者(1.4%)很少。双边毛玻璃或不透明的不透明性(89.6%)是放射学发现的最常见迹象。在大多数患者中观察到了淋巴细胞减少(75.4%)和曙红减少(52.9%)。入院后重度(r = 0.486,p <0.001)和非重度(r = 0.469,p <0.001)患者的血液嗜酸性粒细胞计数与淋巴细胞计数呈正相关。与非重症患者相比,重症患者与D-二聚体,C反应蛋白和降钙素原水平显着相关(所有p <0.001)。

总之,对140例住院的COVID-19病例进行的详细临床研究表明,嗜酸性粒细胞减少症和淋巴细胞减少症可能是诊断的潜在指标。过敏性疾病,哮喘和COPD不是SARS-Co的危险因素。

原始出处:

Zhang JJ, Dong X, et al., Clinical characteristics of 140 patients infected by SARS-CoV-2 in Wuhan, China. Allergy. 2020 Feb 19. doi: 10.1111/all.14238.

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    2020-04-03 hukaixun
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    2020-02-25 小刀医生
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    2020-02-25 膀胱癌
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