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Brit J Surg:青年结直肠癌患者数量有所增加!

2017-06-26 xing.T MedSci原创

由此可见,在实施筛查策略时,需要考虑年轻患者直肠癌发病率有所增加。

新西兰是世界上结直肠癌发病率最高的国家之一。近日,外科疾病领域权威杂志British Journal of Surgery上发表了一篇研究文章,该研究的目的是确定新西兰人群在引入全国结直肠癌筛查前肿瘤发病率和肿瘤部位的变化趋势。

研究所用数据来自于国家癌症登记中心,与1995年至2012年期间的人口数据相互链接。研究人员通过线性回归分析评估了根据性别、年龄(小于50岁,50-79岁,80岁以上)和位置(近端结肠、远端结肠和直肠)的结直肠癌发病率。

在50岁以下的患者中,男性中远端结肠肿瘤的发生率每十年增加了14%(发病率比值(IRR为1.14),95%可信区间为1.00-1.30;P=0.042);男性中直肠癌症的发病率增加了18%(IRR为1.18, 1.06-1.32;P=0.002),女性增加了13%(IRR为1.13, 1.02-1.26;P=0.023)。在那些50-79岁的受试者中,每十年男性和女性近端结肠、远端结肠和直肠癌的发生率有所降低。在80岁及以上受试者中,女性近端结肠癌发病率每十年增加了19%(IRR为1.19, 1.13-1.26;P<0.001)以及在男性中增加了25%(IRR为1.25, 1.18-1.32;P<0.001);在女性中,远端结肠癌发病率下降了8%(IRR为0.92, 0.86-0.98;P=0.012),直肠癌也是一样的(IRR为0.92, 0.86-0.97;P=0.005)。

由此可见,在实施筛查策略时,需要考虑年轻患者直肠癌发病率有所增加。

原始出处:


J. Gandhi,et al. Population-based study demonstrating an increase in colorectal cancer in young patients. British Journal of Surgery.2017. http://onlinelibrary.wiley.com/doi/10.1002/bjs.10518/full

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    2017-07-01 大爰

    学习并分享!!

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  2. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-27 luominglian113

    学习了,谢谢分享

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  4. [GetPortalCommentsPageByObjectIdResponse(id=217305, encodeId=b4b921e3050d, content=学习并分享!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Sat Jul 01 09:27:53 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1452927, encodeId=817c145292ed6, content=<a href='/topic/show?id=098ee8679ad' target=_blank style='color:#2F92EE;'>#结直肠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78679, encryptionId=098ee8679ad, topicName=结直肠)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=9ace5575596, createdName=crystal0564, createdTime=Wed Jun 28 07:43:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215979, encodeId=16792159e97b, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Tue Jun 27 13:35:37 CST 2017, time=2017-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215662, encodeId=763f21566265, content=学习了分享了, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Jun 26 17:48:31 CST 2017, time=2017-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=215652, encodeId=b8d5215652a5, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Mon Jun 26 17:12:31 CST 2017, time=2017-06-26, status=1, ipAttribution=)]
    2017-06-26 dhzzm

    学习了分享了

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    2017-06-26 三生有幸9135

    学习一下谢谢分享

    0

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