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BMJ:含糖饮料是2型糖尿病独立高危因素

2015-10-04 潘宗海 译 医学论坛网

6月29日《循环》(Circulation)曾在线发表一项最新研究发现,含糖饮料导致全球每年死亡18.4万人,主要死因是糖尿病和心血管疾病。此前也有研究证实含糖饮料的摄入与2型糖尿病有关,这一项meta分析进一步证明含糖饮料与糖尿病之间的关系。为探寻饮用含糖饮料、人造甜味饮料及果汁在肥胖前后与2型糖尿病之间的潜在联系。7月21日发表在《英国医学杂志》(BMJ)的一项研究发现,习惯性饮用含糖甜饮料是

6月29日《循环》(Circulation)曾在线发表一项最新研究发现,含糖饮料导致全球每年死亡18.4万人,主要死因是糖尿病和心血管疾病。此前也有研究证实含糖饮料的摄入与2型糖尿病有关,这一项meta分析进一步证明含糖饮料与糖尿病之间的关系。

为探寻饮用含糖饮料、人造甜味饮料及果汁在肥胖前后与2型糖尿病之间的潜在联系。7月21日发表在《英国医学杂志》(BMJ)的一项研究发现,习惯性饮用含糖甜饮料是2型糖尿病发病的独立高危因素,且独立于肥胖。

研究通过美国和英国含糖饮料的消费来评估这类人群在2型糖尿病患者中的比例。

数据来源:2014年2月以前出版在PubMed、Embase、Ovid及网页上关于对无糖尿病的成年人前瞻性研究。人口归因分数参考了2009年-2010年的美国全国人口调查结果(样本4729代表1.891亿无糖尿病成年人),相对应的参考2008-2012年的英国全国人口调查结果(样本1932代表0.447亿无糖尿病成年人)

综合方法:随机效果荟萃分析,调查分析消费含糖甜饮料的人群归因分数.

结果:预先指定的信息是从17个观察组群中提取(38253例/10126754人年)。发现在肥胖调整前后更多的消费含糖饮料与2型糖尿病的发生率的相关性更高,肥胖调整前为18%,肥胖调整后为13%;相对应的人工甜味饮料为25%和8%;果汁为5%和7%。除了果汁与糖尿病的发生关系较小,含糖饮料和人工甜味饮料都与2型糖尿病的发生关系密切。

在过去10年内,2型糖尿病在美国的发病率为11.0%,180万人群归属于含糖饮料的消费;在英国2型糖尿病的发病率为5.8%,7万9***将归属于含糖饮料的消费。

结论:虽然人工甜味饮料和果汁也表现出与2型糖尿病的发病率呈正相关,但其结果很可能涉及偏差。尽管如此,人工甜饮料和果汁也不是含糖饮料预防2型糖尿病发生的健康替代饮料。从因果关系上讲,长期饮用含糖饮料与新发糖尿病病例数相关联。

原始出处:

Malik VS, Hu FB.Fructose and Cardiometabolic Health: What the Evidence From Sugar-Sweetened BeveragesTells Us. J Am Coll Cardiol. 2015 Oct 6;66(14):1615-24

Imamura F, O'Connor L, Ye Z, Mursu J, Hayashino Y, Bhupathiraju SN, Forouhi NG.Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction. BMJ. 2015 Jul 21;351:h3576. doi: 10.1136/bmj.h3576.

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    2016-07-27 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1847717, encodeId=3582184e717a1, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Jul 27 06:13:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42265, encodeId=5ef242265b5, content=为了积分为了学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:21:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42263, encodeId=3771422634d, content=这个不是很新, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:20:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42264, encodeId=a773422640b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:20:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38875, encodeId=7917388e53e, content=含糖饮料里的糖可不是一般的高, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Wed Oct 14 22:13:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38363, encodeId=ad413836361, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:25:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37695, encodeId=f79e3e6957c, content=含糖是主要问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Oct 05 08:02:00 CST 2015, time=2015-10-05, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    为了积分为了学习

    0

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    2015-11-02 nizongzan

    这个不是很新

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1847717, encodeId=3582184e717a1, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Jul 27 06:13:00 CST 2016, time=2016-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42265, encodeId=5ef242265b5, content=为了积分为了学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:21:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42263, encodeId=3771422634d, content=这个不是很新, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:20:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42264, encodeId=a773422640b, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 14:20:00 CST 2015, time=2015-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38875, encodeId=7917388e53e, content=含糖饮料里的糖可不是一般的高, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Wed Oct 14 22:13:00 CST 2015, time=2015-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38363, encodeId=ad413836361, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 20:25:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37695, encodeId=f79e3e6957c, content=含糖是主要问题, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Oct 05 08:02:00 CST 2015, time=2015-10-05, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    收藏

    0

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    2015-10-14 zhouxue1990

    含糖饮料里的糖可不是一般的高

    0

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    2015-10-11 hlycom3356

    感谢作者分享

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    2015-10-05 lovetcm

    含糖是主要问题

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