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J Gerontol A-Biol:限制卡路里摄入量可以大幅延长人类寿命

2017-05-23 Heather_z727 来宝网

一项最新研究表明,限制卡路里摄入量可能减缓衰老。先前的研究已经表明,限制卡路里摄入量可以减缓蠕虫,苍蝇和老鼠的老化,杜克大学的研究人员想看看这样做是否可以减缓人类的生物老化。

【限制卡路里,延长生命?】一项最新研究表明,限制卡路里摄入量可能减缓衰老。先前的研究已经表明,限制卡路里摄入量可以减缓蠕虫,苍蝇和老鼠的老化,杜克大学的研究人员想看看这样做是否可以减缓人类的生物老化。

来自杜克大学的研究人员表示:“生物老化是随着年龄的增加,身体各项机能逐渐退行,恶化的缓慢过程。如果我们可以减缓生物老化的速度,就可能会阻止或至少推迟与年龄相关的退行性疾病的开始时间。”这是研究人员在一次大学新闻发布会上发表的观点。

参与此次试验的参与者共有220人,研究人员将他们分成两组,其中,145人限制卡路里的数量,并且平均减少12%,另一组的75人没有限制卡路里摄入量,检测实验为两年。研究开始的时候,两组的参与者的平均生物年龄是37岁,和他们的实际年龄38岁非常接近。生理年龄计算的数据,包括总胆固醇,血压和血红蛋白水平等决定。

在两年的随访中,卡路里限制组的生理年龄平均每十二个月增减0.11岁,而在未进行卡路里限制的对照组中,参与者每十二个月平均增长0.71岁。这在统计学上是显着的差异。

研究人员补充道:“我们的研究首次对卡路里的摄入量和人类衰老联系在一起,这一发现为我们带来了极大的灵感,我们可以通过模仿卡路里限制法的治疗方案来预防慢性疾病的发展和发生,有效的延缓人类的衰老。”

原始出处:

Daniel W. Belsky, Kim M. Huffman,Carl F. Pieper, et al. Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis. J Gerontol A Biol Sci Med Sci glx096.2017. DOI: https://doi.org/10.1093/gerona/glx096.

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    2018-02-20 lmm397
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    2018-01-16 sunylz
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