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J Endod:眼球颜色与牙科注射疼痛有关?一项预期的随机单盲试验

2018-03-11 lishiting MedSci原创

近来研究发现,疼痛感与发色为红及不同颜色的眼球存在一定的相关性。对于这些与疼痛相关生物标记物的进一步研究有助于我们理解相关通路的潜在基因组成。另外,基于眼球的颜色,也有助于临床判断一个病人在进行牙科治疗时是否更有可能会发生疼痛。这篇研究的目的是为了调查眼球的颜色与健康、无症状的感觉到注射疼痛的白人女性之间是否存在联系。

近来研究发现,疼痛感与发色为红及不同颜色的眼球存在一定的相关性。对于这些与疼痛相关生物标记物的进一步研究有助于我们理解相关通路的潜在基因组成。另外,基于眼球的颜色,也有助于临床判断一个病人在进行牙科治疗时是否更有可能会发生疼痛。这篇研究的目的是为了调查眼球的颜色与健康、无症状的感觉到注射疼痛的白人女性之间是否存在联系。

研究纳入了300名健康的成年白人女性患者,其中133名患者的眼球为黑色,167名为浅色。通过Corah牙科焦虑量表评价患者的牙科治疗焦虑程度。受试者头戴黑色墨镜遮挡眼球颜色,并接受右侧上颌侧切牙注射一支含1:100,000肾上腺素的2%利多卡因。随后,患者在170-mm Heft-Parker视觉模拟量表上标定其注射疼痛评分。由3名独立的观察者对患者眼球拍照并按照黑色和浅色进行分组。使用方差分析和Tukey-Kramer检验对注射疼痛进行比较和评估。

结果显示,注射疼痛在黑色和浅色眼球的受试者之间不存在明显差异。

结论:不能用眼球颜色预估白人女性的注射疼痛。因此,眼球颜色不能用于临床判断一个病人在进行牙科治疗时是否更有可能会发生疼痛。

原始出处:

Hyde J, Fowler S, et al. Is Eye Color Related to Dental Injection Pain? A Prospective, Randomized, Single-blind Study. J Endod. 2018 Mar 2. pii: S0099-2399(18)30044-X. doi: 10.1016/j.joen.2018.01.009.

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    2018-09-04 刘阔
  2. [GetPortalCommentsPageByObjectIdResponse(id=1684053, encodeId=0e0a16840530a, content=<a href='/topic/show?id=a9fee2770d0' target=_blank style='color:#2F92EE;'>#眼球#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72770, encryptionId=a9fee2770d0, topicName=眼球)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a38928025675, createdName=刘阔, createdTime=Tue Sep 04 12:54:00 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461329, encodeId=413814613297c, content=<a href='/topic/show?id=67356e62003' target=_blank style='color:#2F92EE;'>#牙科#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67620, encryptionId=67356e62003, topicName=牙科)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2d786418402, createdName=xzw115, createdTime=Tue Mar 13 01:54:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295195, encodeId=e8d229519503, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Mar 11 13:40:37 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295177, encodeId=0d2b2951e785, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Mar 11 12:35:13 CST 2018, time=2018-03-11, status=1, ipAttribution=)]
    2018-03-13 xzw115
  3. [GetPortalCommentsPageByObjectIdResponse(id=1684053, encodeId=0e0a16840530a, content=<a href='/topic/show?id=a9fee2770d0' target=_blank style='color:#2F92EE;'>#眼球#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72770, encryptionId=a9fee2770d0, topicName=眼球)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a38928025675, createdName=刘阔, createdTime=Tue Sep 04 12:54:00 CST 2018, time=2018-09-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461329, encodeId=413814613297c, content=<a href='/topic/show?id=67356e62003' target=_blank style='color:#2F92EE;'>#牙科#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67620, encryptionId=67356e62003, topicName=牙科)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2d786418402, createdName=xzw115, createdTime=Tue Mar 13 01:54:00 CST 2018, time=2018-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295195, encodeId=e8d229519503, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sun Mar 11 13:40:37 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=295177, encodeId=0d2b2951e785, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Mar 11 12:35:13 CST 2018, time=2018-03-11, status=1, ipAttribution=)]
    2018-03-11 131****1460

    学习了受益匪浅

    0

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    2018-03-11 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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