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PLOS ONE:甜味剂改变肠道微生物群

2018-07-07 海北 MedSci原创

非营养性甜味剂(NNS)广泛用于各种食品和软饮料中。越来越多的证据表明,NNS可导致代谢功能障碍,并可影响体重,葡萄糖耐量,食欲和味觉敏感性。

非营养性甜味剂(NNS)广泛用于各种食品和软饮料中。越来越多的证据表明,NNS可导致代谢功能障碍,并可影响体重,葡萄糖耐量,食欲和味觉敏感性。几种NNS也已显示出对体外和体内细菌生长具有重大影响。
最近,来自悉尼大学的研究人员研究了各种NNS对肠道细菌,大肠杆菌,以及肠道细菌门拟杆菌和厚壁菌的生长的影响,这些菌群间的平衡与肠道健康有关。
研究人员发现,合成甜味剂乙酰磺胺酸钾,糖精和三氯蔗糖均发挥强烈的抑菌作用。研究人员还发现,天然NNS甜叶菊中的活性成分莱鲍迪甙A也具有相似的抑菌特性,并且在不同大肠杆菌菌株中,NNSs的抑菌作用也不同。
在饲喂食物的小鼠中,三氯蔗糖增加了厚壁菌,并且当在高脂肪饮食的情况下提供三氯蔗糖时,研究人员观察到对厚壁菌的协同作用。
总之,该数据显示NNS具有直接的抑菌作用,可以改变体内肠道微生物群。

原始出处:
Wang QP et al. Non-nutritive sweeteners possess a bacteriostatic effect and alter gut microbiota in mice. PLOS ONE 2018, DOI: 10.1371/journal.pone.0199080

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    2018-07-10 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-07-07 猫窝

    受益了

    0

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    2018-07-07 1e17414fm02(暂无匿称)

    学习

    0

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    2018-07-07 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

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    2018-07-07 zb1235672

    学习了!!!!!

    0

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