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J Cardiovasc Electrophysiol:老年房颤患者选择消融术治疗似乎也是安全的

2022-08-03 MedSci原创 MedSci原创

房颤(AF)消融术在世界范围内的应用越来越多。随着对房颤消融术的舒适度提高,该手术越来越多地用于年龄较大和有较多合并症的患者。

房颤(AF)消融术在世界范围内的应用越来越多。随着对房颤消融术的舒适度提高,该手术越来越多地用于年龄较大和有较多合并症的患者。然而,老年人,尤其是大于75岁的老年人,房颤消融术的安全性和疗效是否与年轻人相当,目前还没有得到很好的证实。近日,发表于J Cardiovasc Electrophysiol的一项系统回顾和荟萃分析比较了75岁以上接受房颤消融术的患者与年轻患者的疗效和安全性情况。

研究人员检索了EMBASE、Medline、PubMed和Cochrane数据库截止至2021年9月收录的相关文章。纳入比较房颤导管消融的成功率和75岁以上与75岁以下患者的所有并发症发生率的研究。使用DerSimonian和Laird的随机效应、通用反方差法提取并合并各个研究的效果估计。

 

结果,共有27项观察性研究被纳入分析,包括363,542名接受房颤消融术的患者。与75岁以上的患者和年轻患者相比,老年患者和年轻患者的消融成功率没有差异(集合OR 0.85:95% CI:0.69-1.05,p = 0.131)。另一方面,老年人的房颤消融与较高的并发症发生率有关(集合OR 1.42: 95% CI:1.21-1.68, p < 0.001)。

综上所述,该研究结果表明,尽管在老年人群中发现了较高的并发症发生率,但在大于75岁的老年人和非老年人之间,房颤消融的效果相似。应适当选择房颤消融的对象,尤其是老年人群,以避免有害的结果。危险信号提供了一个可以改善程序结果的机会,以改进老年患者房颤消融术的治疗。

原始出处:

Narut Prasitlumkum, et al., Catheter ablation for atrial fibrillation in the elderly >75 years old: Systematic review and meta-analysis. J Cardiovasc Electrophysiol. 2022 Jul;33(7):1435-1449. doi: 10.1111/jce.15549.

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    2023-06-30 quxin068
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    2022-08-29 杨大笛

    学习了

    0

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