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J Dent Res:头颈鳞状细胞癌的精准医疗

2018-05-21 lishiting MedSci原创

精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法,它对于每一名患者都是独特的。它可以推进患者对不同疾病易感性及治疗反应的层化形成。

精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法,它对于每一名患者都是独特的。它可以推进患者对不同疾病易感性及治疗反应的层化形成。共享数据库和提高信息整合的新技术系统工具能使保健医疗提供者为患者提供更加准确的预测及定制疾病的预防和治疗策略。虽然精准医疗在大多数医学领域的作用有限,但它已被证实是一种越来越成功的癌症治疗方法。尽管早期靶向异常信号通路或阻断驱动肿瘤发展进程(如血管发生)抑制剂的方法具有一定的潜力,但是有限的成功意味着还需要发现新的更加可靠的生物标记物和治疗目标以预测对疗法的反应并获得更好的健康结果。近来,使用免疫诱导抗体的成功刺激了学者们对应用精准免疫疗法治疗头颈鳞状细胞癌产生了更多关注。二代测序可以精确分析肿瘤浸润淋巴细胞的模式,它受益于合理设计的组合方法,从而更有希望鉴定出低免疫原性癌。总之,对肿瘤的持续探索将揭示新的靶向目标,以提高治疗效果并实现头颈癌的精确治疗。原始出处:Polverini PJ, D'Silva NJ, et al. Precision Therapy of Head and Neck Squamous Cell Ca

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level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Tue May 22 07:58:13 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317395, encodeId=1dad31e39577, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRk75KAEKrLGic0S0IvH1aNynsEFQWiaNKdtzvtwj2kafCoPg2icYVbrfBCFiaS74X1uEiaaTTY1H9Xyem/0, createdBy=cec11614828, createdName=chunjianf, createdTime=Tue May 22 06:50:26 CST 2018, time=2018-05-22, status=1, ipAttribution=), 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likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 21 22:35:50 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317302, encodeId=b02e31e3027b, content=精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法.它对于每一名患者都是独特的.它可以推进患者对不同疾病易感性及治疗反应的层化形成., beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 21 22:21:10 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317295, encodeId=3af831e295a3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-22 kafei

    了解一下谢谢

    0

  5. 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level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Tue May 22 07:58:13 CST 2018, time=2018-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317395, encodeId=1dad31e39577, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRk75KAEKrLGic0S0IvH1aNynsEFQWiaNKdtzvtwj2kafCoPg2icYVbrfBCFiaS74X1uEiaaTTY1H9Xyem/0, createdBy=cec11614828, createdName=chunjianf, createdTime=Tue May 22 06:50:26 CST 2018, time=2018-05-22, status=1, ipAttribution=), 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-22 chunjianf

    学习了.谢谢分享

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-21 131****2916

    不错的文章值得学习研究

    0

  7. 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likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 21 22:35:50 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317302, encodeId=b02e31e3027b, content=精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法.它对于每一名患者都是独特的.它可以推进患者对不同疾病易感性及治疗反应的层化形成., beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 21 22:21:10 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317295, encodeId=3af831e295a3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-21 orangesking

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-21 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

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objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-21 有备才能无患

    精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法.它对于每一名患者都是独特的.它可以推进患者对不同疾病易感性及治疗反应的层化形成.

    0

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likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Mon May 21 22:35:50 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317302, encodeId=b02e31e3027b, content=精准医疗是考虑到遗传变异性和环境及生活方式的影响而形成的一种疾病治疗和预防方法.它对于每一名患者都是独特的.它可以推进患者对不同疾病易感性及治疗反应的层化形成., beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Mon May 21 22:21:10 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317295, encodeId=3af831e295a3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Mon May 21 21:51:33 CST 2018, time=2018-05-21, status=1, ipAttribution=)]
    2018-05-21 清风拂面

    谢谢分享学习

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