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Clin Chem:床旁检测c反应蛋白,葡萄糖,血红蛋白测试的可交换性全血外部质量评估材料

2019-08-03 不详 MedSci原创

一般来说,外部质量评估<span lang="EN-US" style="font-size:12.0pt;mso-bidi-font-size:14.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;; mso-fareast-font-family:宋体;mso-bidi-font-family:&quot;Times New

一般来说,外部质量评估(EQA)的最佳情况是使用可交换材料。之前对于床旁检测全血检测材料的可交换性尚无研究。本研究的目的是确定在挪威常用的POC仪器的挪威质量改进实验室检查(Noklus)组织的内部全血EQA材料用于C-反应蛋白(CRP),葡萄糖和血红蛋白的可交换性,并确定为每种分析物使用共同目标值的可能性。

本研究遵循临床与实验室标准协会指南进行研究。EQA材料是稳定的EDTA静脉全血,包含不同浓度的分析物。使用17POC3种医院仪器对EQA材料和本地常规患者样本进行分析。采用戴明回归分析对各仪器之间的可换性进行评估,预测区间为95%

研究显示,EQA材料对所有CRP和血红蛋白POC仪器均具有可交换性,而对葡萄糖,在最低浓度分析[126.0 mg/dL (7.0 mmol/L)]和所有浓度分析的3POC仪器均可交换。

使用CRP和血红蛋白POC仪器的Noklus EQA的结果与参考目标值相似,而使用葡萄糖POC仪器的结果仍然与方法特异性目标值相比较接近。可以计算可交换葡萄糖POC仪器与参考目标值之间的系统偏差,同时,这些额外的信息可以提供给这些参与者和制造商。

原始出处:

Tone Bukve, Sverre Sandberg, Commutability of a Whole-Blood External Quality Assessment Material for Point-of-Care C-Reactive Protein, Glucose, and Hemoglobin Testing

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2020-04-24 howi
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