Baidu
map

PLoS One:爆炸引起耳鸣的电生理评估和药物治疗

2021-01-27 AlexYang MedSci原创

耳鸣是对声音的幻觉,常作为听觉创伤的临床后遗症出现。

耳鸣是对声音的幻觉,常作为听觉创伤的临床后遗症出现。

最近,有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。虽然确切的机制尚不清楚,但 "中枢增益理论 "认为,耳鸣是中枢听觉系统的增益(或神经放大)异常增加的感知指标,以补偿来自耳蜗的感觉输入的外周损失。他们来自vehicle-treated大鼠的数据支持了这一理论;即爆破诱导的耳蜗协同病变与中枢产生的ABR波V振幅与外周产生的波I振幅之比的不平衡升高相关,从而导致耳鸣的行为证据。Logistic回归模型表明,ABR波V/I振幅比值可作为客观识别耳鸣的可靠指标。此外,爆炸暴露大鼠的组织病理学检查显示了中枢听觉通路中关键可塑性因子表达模式的耳鸣相关变化,包括Arc/Arg3.1的逐渐损失。

最后,研究人员使用N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)的配方作为解决爆炸诱导的神经退化的治疗方法,表现出了IHC带状突触的保存或恢复、ABR波V/I振幅比的正常化,以及爆炸暴露大鼠耳鸣的行为证据减少

原始出处:

Jianzhong Lu , Matthew B West , Xiaoping Du et al. Electrophysiological assessment and pharmacological treatment of blast-induced tinnitus. PLoS One. Jan 2021

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
    2021-01-27 Baodongxu

    N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方

    1

    展开1条回复
  2. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
    2021-01-27 Jessie Zhang

    有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=920322, encodeId=0f2d92032208, content=N-乙酰半胱氨酸(NAC)和2,4-二磺酸苯基-N-叔丁基尼通二钠(HPN-07)配方, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=1, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210315/480e12f811f44bc39b347d2521d56e86/67d0e6d503124ea685205b567af3dffd.jpg, createdBy=f9435296193, createdName=Baodongxu, createdTime=Wed Jan 27 16:14:41 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798597, encodeId=ad4f1e985971a, content=<a href='/topic/show?id=2a916954efe' target=_blank style='color:#2F92EE;'>#生理评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69547, encryptionId=2a916954efe, topicName=生理评估)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cbcc223, createdName=cooco, createdTime=Sun Nov 21 20:33:05 CST 2021, time=2021-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1790403, encodeId=0f9b1e9040385, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Wed Apr 21 05:33:05 CST 2021, time=2021-04-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295779, encodeId=d6f01295e7995, content=<a href='/topic/show?id=86158052809' target=_blank style='color:#2F92EE;'>#耳鸣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80528, encryptionId=86158052809, topicName=耳鸣)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3609256, createdName=zhu_jun9837, createdTime=Fri Jan 29 05:33:05 CST 2021, time=2021-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920340, encodeId=6a7392034071, content=有研究人员为了开发一种客观的测试和治疗耳鸣的方法,在爆炸暴露的大鼠中了相关研究,并重点测量听觉脑干反应(ABRs)、听觉惊吓反应的前脉冲抑制和耳蜗内毛细胞(IHCs)的突触前带状密度。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/5008534db22c474a844fbd107ff83af2/d3e20fc133b542208ff15e7f2b575329.jpg, createdBy=c7015311102, createdName=Jessie Zhang, createdTime=Wed Jan 27 17:19:57 CST 2021, time=2021-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=920295, encodeId=9b2b92029570, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLjLkLnjZXzaJYRekHibke5aibERD9icn9d4afvFXepAPHH2WeWibGbp8G0nic0dlczzFic70zU8YNWsW1A/132, createdBy=355d5328553, createdName=飞了, createdTime=Wed Jan 27 14:59:32 CST 2021, time=2021-01-27, status=1, ipAttribution=)]
    2021-01-27 飞了

    0

相关资讯

JAMA Psychiatry:重度抑郁症的药物和心理序贯联合治疗

序贯的心理治疗整合似乎是一种有效的策略,在预防复发和方面效果较为理想。

《晚期非小细胞肺癌抗血管生成药物治疗中国专家共识(2020版)》正式发布,助力晚期NSCLC临床治疗水平提升

在2020年CSCO即将到来之际,9月14日,由中国临床肿瘤学会(CSCO)血管靶向治疗专家委员会及非小细胞肺癌专家委员会主导撰写的《晚期非小细胞肺癌抗血管生成药物治疗中国专家共识(2020版)》(以

Clin Cancer Res:CEACAM5的调控及抗CEACAM5-SN38抗体-药物结合物在神经内分泌前列腺癌中的治疗效果

神经内分泌前列腺癌(NEPC)是一种侵袭性的去势抵抗性前列腺癌(CRPC),目前缺乏有效的治疗方法。研究人员之前鉴定了类癌抗原相关的细胞粘附分子5(CEACAM5),可作为一个很有前景的NEPC细胞表

Genes Dev :二甲双胍再添新功能,可逆转肝脏炎症

二甲双胍是治疗Ⅱ型糖尿病的一线药物,在全世界范围内有数亿名患者在使用。与此同时,除了降血糖之外,二甲双胍还能改善血脂代谢、减肥、减少心血管并发症发生几率,甚至有抗衰老和抗肿瘤的效用。

Lancet Neurology:未破裂脑动静脉畸形(ARUBA)药物联合介入治疗与单纯药物治疗的比较:一项多中心、非盲、随机对照试验的最终随访

一项未破裂的脑动静脉畸形(ARUBA)的随机试验中,在预先指定的中期分析中表明,在预防症状性中风或死亡方面,单纯的药物治疗优于药物治疗和介入治疗的联合治疗。

JAHA:急性冠脉综合症患者焦虑和疼痛药物治疗与创伤后应激障碍症状风险的关系

尽管苯二氮卓类药物在ACS期间有短期抗焦虑作用,但可能会增加ACS诱导的PTSS风险,从而影响患者的生活质量和预后。

Baidu
map
Baidu
map
Baidu
map