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新材料或让骨折手术的钢板和螺栓走出历史

2017-06-20 贾朝娟 环球医学

丝绸与钢铁本来是牛马不相及的两种材料,而一位教授的奇思妙想将二者联系在了一起,以解决骨折患者需二次手术的难题。钢板和螺栓通常是外科医生唯一用于固定骨折骨的工具。问题是钢可以阻止新骨细胞修复骨折。通过进一步手术去除钢铁可能会使骨骼变脆。材料科学家刘婉娴教授说,这个障碍是一个真正的问题,需要新材料来替代钢铁。PLA为近年来发现的一种可生物降解聚合物,已用于某些食品包装和医疗植入物中。如果PLA可以将骨

丝绸与钢铁本来是牛马不相及的两种材料,而一位教授的奇思妙想将二者联系在了一起,以解决骨折患者需二次手术的难题。钢板和螺栓通常是外科医生唯一用于固定骨折骨的工具。问题是钢可以阻止新骨细胞修复骨折。通过进一步手术去除钢铁可能会使骨骼变脆。材料科学家刘婉娴教授说,这个障碍是一个真正的问题,需要新材料来替代钢铁。

PLA为近年来发现的一种可生物降解聚合物,已用于某些食品包装和医疗植入物中。如果PLA可以将骨头固定在一起,然后随着时间的推移被身体吸收,骨细胞可以进入骨骼并治愈骨折,从而避免二次手术的需要。但到目前为止,PLA已经被证明太脆弱了,不能增强骨骼。

刘教授2007年遇见了这一问题的可能解决方案。禽流感在香港爆发,一百多万只鸡被杀以阻止传播。他想知道鸡羽毛有没有用处,将动物纤维与其他材料混合的想法正是起源于此。但是,羽毛纤维难以净化,刘的团队发现了一种更容易使用的替代方法,那就是蚕丝。

2008年,刘教授领衔的香港理工大学团队将蚕丝纤维与PLA结合,发现聚合物变得更加硬了。添加约6%的丝纤维使得可生物降解的聚合物与骨骼一样坚固。另外,该团队还发现细胞可以在材料的周围生长,随着它的降解,显示出应用于骨折患者的潜在可能性。

刘教授表示,现阶段我们取得了很大的成就,但还有很长的路要走。

刘教授现在正在处理正确的销钉和螺钉的设计,预计该材料有一天可以通过扫描骨断裂和3-D打印为患者量身打造完美的骨骼形状。目前正在寻找澳大利亚的合作者着手进行动物试验,并最终将新材料应用于患者。如果研究成功,骨折患者的修复手术将不再需要钢板和螺栓!

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    2017-06-22 cathymary
  2. [GetPortalCommentsPageByObjectIdResponse(id=1526210, encodeId=87601526210ea, content=<a href='/topic/show?id=84d03692056' target=_blank style='color:#2F92EE;'>#历史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36920, encryptionId=84d03692056, topicName=历史)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=131011702315, createdName=cathymary, createdTime=Thu Jun 22 13:25:00 CST 2017, time=2017-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213386, encodeId=e913213386bd, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Wed Jun 21 08:00:48 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213318, encodeId=d53a2133187f, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jun 21 05:57:12 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213286, encodeId=46e8213286b4, content=希望这样的材料早点问世, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Jun 21 00:10:26 CST 2017, time=2017-06-21, status=1, ipAttribution=)]
    2017-06-21 189****7206

    学习了谢谢分享。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1526210, encodeId=87601526210ea, content=<a href='/topic/show?id=84d03692056' target=_blank style='color:#2F92EE;'>#历史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36920, encryptionId=84d03692056, topicName=历史)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=131011702315, createdName=cathymary, createdTime=Thu Jun 22 13:25:00 CST 2017, time=2017-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213386, encodeId=e913213386bd, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Wed Jun 21 08:00:48 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213318, encodeId=d53a2133187f, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jun 21 05:57:12 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213286, encodeId=46e8213286b4, content=希望这样的材料早点问世, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Jun 21 00:10:26 CST 2017, time=2017-06-21, status=1, ipAttribution=)]
    2017-06-21 changjiu

    学习了谢谢

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1526210, encodeId=87601526210ea, content=<a href='/topic/show?id=84d03692056' target=_blank style='color:#2F92EE;'>#历史#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36920, encryptionId=84d03692056, topicName=历史)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=131011702315, createdName=cathymary, createdTime=Thu Jun 22 13:25:00 CST 2017, time=2017-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213386, encodeId=e913213386bd, content=学习了谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5Kzuf9u71gZhPYMiajRtENwicoAABeQtfXOlic8ibhYSy6DvJZWUDVtjRvTfqBffr1XJ6JLtFB5kHicthl/0, createdBy=08bb2061153, createdName=189****7206, createdTime=Wed Jun 21 08:00:48 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213318, encodeId=d53a2133187f, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Wed Jun 21 05:57:12 CST 2017, time=2017-06-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=213286, encodeId=46e8213286b4, content=希望这样的材料早点问世, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Wed Jun 21 00:10:26 CST 2017, time=2017-06-21, status=1, ipAttribution=)]
    2017-06-21 飛歌

    希望这样的材料早点问世

    0

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