Baidu
map

J Clin Periodontol:牙龈卟啉单胞菌或是中国侵袭性牙周炎的主要致病菌?

2015-10-11 sunshine 译 MedSci原创

J Clin Periodontol:牙龈卟啉单胞菌或是中国侵袭性牙周炎的主要致病菌?侵袭性牙周炎是发生于全身健康者的进展迅速、有家族聚集性、不同于慢性牙周炎的一类牙周炎,根据病变的累及范围可分为局限型和广泛型。侵袭性牙周炎虽多发于年青人,但也可见成年人。本病一般来说发展较迅猛,但也可转为间歇性的静止期。本研究旨在探究侵袭性牙周炎中国患者的牙周致病菌组成,并对比侵袭性牙周炎患者之间以及患者与家人之

侵袭性牙周炎是发生于全身健康者的进展迅速、有家族聚集性、不同于慢性牙周炎的一类牙周炎,根据病变的累及范围可分为局限型和广泛型。侵袭性牙周炎虽多发于年青人,但也可见于成年人。本病一般来说发展较迅猛,但也可转为间歇性的静止期(修复期)。


本研究旨在探究侵袭性牙周炎中国患者的牙周致病菌组成,并对比侵袭性牙周炎患者之间以及患者与家人之间细菌组成的相似性。

研究人员采集了10名侵袭性牙周炎患者及其10名直系亲属的龈下菌斑和唾液样本,10名直系亲属均为慢性牙周炎患者。PCR扩增细菌16S rRNA基因的V1-V3超变区,并进行454高通量测序。

结果发现,龈下菌斑中,家庭成员间未加权UniFrac距离远低于无血缘关系的参与者(P=0.039)。与其直系亲属相比,侵袭性牙周炎患者龈下菌斑及唾液中微生物的种类明显较低。侵袭性牙周炎患者龈下菌斑中牙龈卟啉单胞菌的相对丰都较高(约35.88%)。同一侵袭性牙周炎患者的龈下菌斑和唾液样本中的牙龈卟啉单胞菌以及红色复合体(牙龈卟啉单胞菌、齿垢密螺旋体、福赛坦氏菌)的相对丰度显著相关(分别为ρ= 0.687,0.678)。

本研究展示的是中国侵袭性牙周炎患者及其家庭成员的口腔微生物群结构关系,而牙龈卟啉单胞菌可能是中国侵袭性牙周炎患者的主要致病菌。

原始出处:

Li Y, Feng X et al.Oral Microbiome in Chinese Patients with Aggressive Periodontitis and Their Family Members. J Clin Periodontol. 2015 Sep 28. doi: 10.1111/jcpe.12463.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
    2016-07-25 feather89
  3. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
    2015-10-13 sunyl07
  5. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
    2015-10-13 cooco
  8. [GetPortalCommentsPageByObjectIdResponse(id=125014, encodeId=b95e12501434, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:46:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725895, encodeId=08d11e25895a3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jul 25 07:59:00 CST 2016, time=2016-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361030, encodeId=8770136103035, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366242, encodeId=d325136624247, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450428, encodeId=68661450428e8, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536746, encodeId=7abb1536e4634, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626189, encodeId=63511626189d3, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Tue Oct 13 05:59:00 CST 2015, time=2015-10-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38780, encodeId=d1b938e802f, content=目前主流的观点还是Aa,本文的研究样本量有点小, beContent=null, objectType=article, channel=null, level=null, likeNumber=204, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Mon Oct 12 18:18:00 CST 2015, time=2015-10-12, status=1, ipAttribution=)]
    2015-10-12 xiaotaiyang1

    目前主流的观点还是Aa,本文的研究样本量有点小

    0

相关资讯

BMC Oral Health:侵袭性牙周炎的治疗:辅助应用抗生素or PDT,哪个更有效?

 本研究的目的是为了评估非手术治疗方法联合全身抗生素(AB)应用或光动力疗法(PDT)对侵袭性牙周炎(AgP)患者龈沟液中基质金属蛋白酶8(MMP-8)和基质金属蛋白酶9(MMP-9)浓度的影响。研究纳入了36名侵袭性牙周炎患者,将其随机分配为两组。一组患者在接受全身抗生素(如阿莫西林+甲硝唑)用药后,进行洁刮治和根面平整(SRP);另一组患者则接受SRP+PDT治疗。治疗前及治疗后第3

J Periodontol:端粒酶的表达与牙周炎有关

J Periodontol:端粒酶的表达与牙周炎有关本研究的目的是为了评估相对于健康人,慢性牙周炎(CP)以及侵袭性牙周炎(AgP)患者体内端粒逆转录酶(hTERT)的表达。 研究纳入79名研究对象,包括30名健康人,30名CP患者以及19名AgP患者。收集每位研究对象的牙龈组织,并通过蛋白质印迹法和免疫组织化学法来评估其hTERT的表达。收集研究对象的龈沟液(GCF)样本,进行反转录聚合酶链式

Baidu
map
Baidu
map
Baidu
map