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DIABETOLOGIA:糖尿病足溃疡的高危人群中截肢生存情况如何?

2018-12-02 MedSci MedSci原创

本研究目的是研究糖尿病足溃疡高风险人群(“高风险足”)的无截肢生存率,并比较高风险足的不同亚类。 2008年1月至2011年12月期间,研究人员从苏格兰的糖尿病登记处(Scottish Care Information-Diabetes:N  = 247,278)中确认了17,353名患有糖尿病和高危人群的个体。从基线开始对参与者随访长达2年,并将其分为三组:(1)无溃疡的患者,(2)活动性

本研究目的是研究糖尿病足溃疡高风险人群(“高风险足”)的无截肢生存率,并比较高风险足的不同亚类。

20081月至201112月期间,研究人员从苏格兰的糖尿病登记处(Scottish Care Information-DiabetesN  = 247,278)中确认了17,353名患有糖尿病和高危人群的个体。从基线开始对参与者随访长达2年,并将其分为三组:(1)无溃疡的患者,(2)活动性溃疡患者或(3)溃疡愈​​合者。先前轻微或大截肢的参与者被排除在外。加速失效时间模型用于比较三个暴露组之间长达2年的无截肢存活率。

结果显示,所有糖尿病合并高危人群的2年无截肢生存率为84.5%。在该研究组中,270名患者(10.0%)截肢,2424名(90.0%)在2年随访期间死亡。与没有先前溃疡的患者(p  <0.0001)相比,在基线时有活动和愈合的先前溃疡的患者的2年无截肢生存率显著性降低。溃疡愈合,活动性溃疡或无基线溃疡的患者在2年内死亡的百分比分别为22.8%,16%和12.1%。

处于足部溃疡高风险的人群中,死亡风险高达截肢风险的九倍。溃疡愈合的糖尿病患者死亡率高于活动性溃疡患者。然而,患有活动性溃疡的人截肢的风险最高。

原始出处:

Thenmalar Vadiveloo, Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2018-12-03 haige

    处于足部溃疡高风险的人群中,死亡风险高达截肢风险的九倍。溃疡愈合的糖尿病患者死亡率高于活动性溃疡患者。然而,患有活动性溃疡的人截肢的风险最高。

    0

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    2018-12-03 misszhang

    谢谢MedSci提供最新的资讯

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