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SCI REP:开放无症状的睑板腺功能障碍患者心血管疾病的危险因素!

2017-07-10 xing.T MedSci原创

总之,这项结果表明无症状的MGD可以作为心血管疾病的一个指标。

管理血管疾病(CVD)的危险因素是预防血管疾病的关键。近日,Scientific reports 杂志上发表了一篇研究文章,该研究旨在通过引入无症状睑板腺功能障碍(MGD)来预防心血管疾病,MGD与多种心血管疾病危险因素相关联的疾病,作为中年人群心血管疾病的早期指标。

有或无无症状MGD的参与者接受了标准化的问卷调查、体格检查和实验室检查。一名眼科医生在眼睑边缘利用裂隙灯显微镜检查了MGD分级、睑板腺开口与睑板腺分泌物。研究人员采用标准化的技术来测量CVD危险因素的参数。

在调整了年龄和性别后,心血管疾病的危险因素包括血尿酸(P=0.01  )、总胆固醇(TC,P<0.001)、低密度脂蛋白胆固醇(LDL-C,P<0.001,空腹甘油三酯(TG)、空腹甘油三酯(P≤0.001),降低的高密度脂蛋白胆固醇(HDL-C,P=0.04),脂肪肝的存在(P=0.008)与无症状的MGD显著相关。逐步Logistic回归分析显示,低密度脂蛋白胆固醇(比值比为1.03,95%可信区间为1.02–1.04)和Fasting TG(比值比为1.01;95%可信区间为1-1.01)水平是无症状的MGD患者的危险因素(P<0.001)。

总之,这项结果表明无症状的MGD可以作为心血管疾病的一个指标。

原始出处:

Alexander Chen,et al. Asymptomatic Meibomian Gland Dysfunction and Cardiovascular Disease Risk Factors in a Middle-Aged Population in Taiwan - A Cross-sectional Analysis.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-05368-z

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    2017-07-15 chunjianf

    学习了,谢谢分享

    0

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    2017-07-15 lou.minghong

    没有看明白!

    0

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  4. 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objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Jul 11 06:46:52 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
    2017-07-11 半夏微凉

    学习了谢谢分享

    0

  7. 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level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Tue Jul 11 09:31:36 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220998, encodeId=36ac220998de, content=学习了新知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Jul 11 09:17:09 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220893, encodeId=7edd22089325, content=了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Jul 11 06:58:20 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220880, encodeId=1f00220880cb, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Jul 11 06:47:28 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220875, encodeId=2a7b2208e510, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Jul 11 06:46:52 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
    2017-07-11 Y—xianghai

    学习了新知识

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Jul 11 06:46:52 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
    2017-07-11 1dd8c52fm63(暂无匿称)

    了解了解

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Jul 11 06:46:52 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
    2017-07-11 龙胆草

    学习谢谢分享

    0

  10. 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content=了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Jul 11 06:58:20 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220880, encodeId=1f00220880cb, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Jul 11 06:47:28 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220875, encodeId=2a7b2208e510, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Tue Jul 11 06:46:52 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
    2017-07-11 刘煜

    学习了谢谢分享

    0

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