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JACC:双侧胸内动脉搭桥术后的预后研究

2020-02-05 不详 MedSci原创

本研究的目的旨在评估双侧胸内动脉(BITA)搭桥术后优势左前降支(LAD)和重要的非LAD靶血管对冠心病患者预后的影响。本研究纳入分析了6127名接受BITA手术的患者,其中2551名患者接受的是一侧胸内动脉移植至LAD,且冠脉造影可评估。经过平均14 ± 8.7年时间的随访,发现优势LAD在有相对不重要的靶标患者中更常见(51% vs. 35%; p < 0.0001),共有179名患者接

本研究的目的旨在评估双侧胸内动脉(BITA)搭桥术后优势左前降支(LAD)和重要的非LAD靶血管对冠心病患者预后的影响。

本研究纳入分析了6127名接受BITA手术的患者,其中2551名患者接受的是一侧胸内动脉移植至LAD,且冠脉造影可评估。经过平均14 ± 8.7年时间的随访,发现优势LAD在有相对不重要的靶标患者中更常见(51% vs. 35%; p < 0.0001),共有179名患者接受了二次胸内动脉移植,其中77名移植至多支重要血管。在多变量分析模型中,二次将胸内动脉移植至多支重要血管与更好的远期预后相关(p = 0.005)。在非LAD优势的患者中,二次移植胸内动脉至不重要的血管与更高的死亡率相关(2.4% vs. 0.51%; p = 0.007)。另外,隐静脉移植与患者远期预后不相关。

研究结果显示,在BITA移植中,绕过多个重要靶点,使胸内动脉供应的心肌最大化,可以提高患者长期存活率。

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    2020-09-25 hbwxf
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    2020-02-07 zzc2214
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