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Radiology:那些CT征象能够提示肺腺癌经气道播散?

2019-04-02 shaosai MedSci原创

本研究旨在识别能够预测与手术切除肺腺癌经气道播散(STAS)的CT征象。

本研究旨在识别能够预测与手术切除肺腺癌经气道播散(STAS)的CT征象。

本研究共纳入了948例行肺腺癌手术切除的患者,并评价是否有STAS。利用患者指标将STAS阳性和STAS阴性匹配比例为1:2.利用多变量Logistic回归分析和ROC曲线评价CT征象(例如实性成分百分比、实性成分最大径、病变密度、位置、边界、形状、假空洞征、钙化、中心低密度征、外周淡磨玻璃密度征、空气支气管征、卫星灶和胸膜牵拉征)。

结果为,本研究共纳入了276例患者,其中129例男性和147例女心。STAS阳性和STAS阴性分别为92例、184例。STAS多常见于实性肿瘤,其次为亚实性肿瘤,最少见于磨玻璃密度灶。STAS也与中心低密度征、边界淡磨玻璃密度、空气支气管征和实性成分百分比具有相关性。实性成分百分比是预测STAS的独立预测指标,以90%为最佳截断值的鉴别敏感性、特异性分别为89.2%、60.3%。

本研究表明,肺腺癌实性成分百分比与经气道播散具有独立相关性。

原始出处:

Kim SK, Kim TJ, Chung MJ,et al.Lung Adenocarcinoma: CT Features Associated with Spread through Air Spaces.Radiology.DOI:10.1148/radiol.2018180431

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    2019-04-05 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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    2019-04-03 一个字-牛

    学习了谢谢分享

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    2019-04-02 329523732

    不错

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    2019-04-02 衣带渐宽

    学习

    0

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