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J Orthop Surg Res：骨缺损修复支架在临床中的应用

2018-03-16 MedSci MedSci原创

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本系统综述旨在总结骨支架在骨缺损修复中的临床应用研究。 通过PubMed数据库搜索相关文章。使用以下关键词和搜索术语：“支架”，“患者”，“诊所”，“骨修复”，“骨再生”，“修复骨缺损”，“骨修复”，“骨关节成形术”和“骨生成”。根据纳入和排除标准筛选这些文章。 结果，PubMed数据库检索共获得373篇文章。筛选后，20篇文章被确定为与本系统综述目的相关。收集生物支架和合成支架的数据。其中八项生

本系统综述旨在总结骨支架在骨缺损修复中的临床应用研究。

通过PubMed数据库搜索相关文章。使用以下关键词和搜索术语：“支架”，“患者”，“诊所”，“骨修复”，“骨再生”，“修复骨缺损”，“骨修复”，“骨关节成形术”和“骨生成”。根据纳入和排除标准筛选这些文章。

结果，PubMed数据库检索共获得373篇文章。筛选后，20篇文章被确定为与本系统综述目的相关。收集生物支架和合成支架的数据。其中八项生物支架的临床研究包括胶原蛋白，明胶和细胞支架用于骨骼愈合。此外，本系统综述还涉及12个关于HAp，TCP，bonelike合成支架的临床研究及其修复骨缺损的复杂支架。

结果表明，大量的临床证据表明应用支架具有良好的促进骨修复和骨生成的能力。然而，理想和可靠的指导原则没有得到充分的应用，该领域的研究数量和质量仍有待提高。

原始出处：

Zeng JH, Liu SW, et al., Scaffolds for the repair of bone defects in clinical studies: a systematic review. J Orthop Surg Res. 2018 Feb 12;13(1):33. doi: 10.1186/s13018-018-0724-2.

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#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1419254, encodeId=646b14192543d, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Sun Mar 18 07:43:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296840, encodeId=ff0329684099, content=感谢分享.学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/03/13/c36860368f59b7f042bac242c6785040.jpg, createdBy=457b1858657, createdName=ms2296823935859672, createdTime=Fri Mar 16 17:54:53 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296835, encodeId=418929683574, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 16 17:09:00 CST 2018, time=2018-03-16, status=1, ipAttribution=)]
    2018-03-18 lfcmxl

    #骨缺损#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1419254, encodeId=646b14192543d, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Sun Mar 18 07:43:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296840, encodeId=ff0329684099, content=感谢分享.学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/03/13/c36860368f59b7f042bac242c6785040.jpg, createdBy=457b1858657, createdName=ms2296823935859672, createdTime=Fri Mar 16 17:54:53 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296835, encodeId=418929683574, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 16 17:09:00 CST 2018, time=2018-03-16, status=1, ipAttribution=)]
    2018-03-16 ms2296823935859672

    感谢分享.学习了!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1419254, encodeId=646b14192543d, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Sun Mar 18 07:43:00 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296840, encodeId=ff0329684099, content=感谢分享.学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/03/13/c36860368f59b7f042bac242c6785040.jpg, createdBy=457b1858657, createdName=ms2296823935859672, createdTime=Fri Mar 16 17:54:53 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296835, encodeId=418929683574, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 16 17:09:00 CST 2018, time=2018-03-16, status=1, ipAttribution=)]
    2018-03-16 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

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