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JAHA:英国研究称:心衰患者第二大死因是感染

2018-10-19 xujing 中国循环杂志

据《美国心脏协会杂志》发表的一项研究,脓毒症是左心室射血分数降低心力衰竭患者死亡的主要原因。

据《美国心脏协会杂志》发表的一项研究,脓毒症是左心室射血分数降低心力衰竭患者死亡的主要原因。

研究人员对在英国四家医院就诊的LVEF<45%的慢性HF患者1802例进行了前瞻性队列研究。

随访10.3年(平均4年),其中737例死亡,其中进行性心衰占30.9%;心脏猝死占15.2%;其他血管疾病占8%;非血管病原因占42.6%。

在非心血管死亡中,研究人员发现55.1%是由败血症引起的,占所有死亡的23.5%,其中呼吸道感染占败血症相关事件的69.9%。

那些死于败血症的人年龄更大,血小板计数更高,并且慢性阻塞性肺病的患病率高于死于其他原因的人。

进一步分析显示,脓毒症死亡与老年、慢性阻塞性肺疾病、男性、血清维生素D水平降低以及高血小板计数独立相关。

研究人员观察到,于其他死亡原因相比,脓毒症死亡更多发生在医院环境比其他死亡(86.1%比49.4%,P<0.001)。

研究者称,脓毒症几乎导致了四分之一的心衰死亡,脓毒症成为继进行性心力衰竭之后第二位死亡原因。

原始出处:Andrew M. N. Walker, Michael Drozd, Marlous Hall, et al. Prevalence and Predictors of Sepsis Death in Patients With Chronic Heart Failure and Reduced Left Ventricular Ejection Fraction. JAHA. 2018;7:e009684

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    2018-10-31 13718711b3m

    非常好的临床经验,学习了,涨知识,值得借鉴,受益匪浅,感谢分享!

    0

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    2018-10-20 zhaohui6731
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    2018-10-19 天地飞扬

    了解一下,谢谢分享!

    0

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    2018-10-19 明月清辉

    谢谢分享,学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=351056, encodeId=39133510568f, content=非常好的临床经验,学习了,涨知识,值得借鉴,受益匪浅,感谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Wed Oct 31 12:46:50 CST 2018, time=2018-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267946, encodeId=e2f3126e946e1, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Oct 20 15:03:00 CST 2018, time=2018-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373431, encodeId=986413e3431df, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Oct 20 15:03:00 CST 2018, time=2018-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=349807, encodeId=ba0834980e9f, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Fri Oct 19 08:29:18 CST 2018, time=2018-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=349791, encodeId=d3c6349e9168, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Fri Oct 19 07:09:48 CST 2018, time=2018-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=349776, encodeId=366c349e76ad, content=谢谢了,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Fri Oct 19 05:59:17 CST 2018, time=2018-10-19, status=1, ipAttribution=)]
    2018-10-19 txqjm

    谢谢了,学习

    0

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