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JAMA Oncology:低脂饮食与乳腺癌生存改善有关,10 年内死亡风险降低 22%

2018-05-28 佚名 康健新视野

5 月 24 日,《JAMA Oncology》发布了一条论文消息,最新的临床随机试验证据指出,平时保持低脂饮食习惯,与乳腺癌死亡风险降低显著相关,乳腺癌患者自诊断后 10 年内全因死亡风险降低 22%。

5 月 24 日,《JAMA Oncology》发布了一条论文消息,最新的临床随机试验证据指出,平时保持低脂饮食习惯,与乳腺癌死亡风险降低显着相关,乳腺癌患者自诊断后 10 年内全因死亡风险降低 22%。

这项研究显示了低脂饮食的又一健康益处,”研究的主要作者、美国加州 City of Hope 医院的 Rowan Chlebowski 教授表示。

关于饮食的健康益处,一直都是大家比较关心的话题。而饮食习惯对乳腺健康的影响,实际上也已经成为了医疗保健领域的热门科普话题。

而本次《JAMA Oncology》的报道,给出了高级别的随机对照研究证据提示,低脂饮食结构,可能会对乳腺癌预后有积极的影响。

研究人员基于美国妇女健康倡议项目下的随机对照试验数据,分析了 40 个临床中心累计约 49,000 名绝经后妇女的长期随访结果,表明了低脂饮食可能带来乳腺癌生存获益的结论。核心数据如下:

这群绝经后妇女人群中,约 40% 患者随机进入到了低脂饮食干预组,每日饮食供热中脂肪热量占比由原来的 30% 以上控制到 20% 以下,剩余患者维持原有饮食习惯不变,作为对照组。

饮食干预研究持续 8 年期间,1,764 名妇女被诊断出乳腺癌。这些乳腺癌患者自从初始诊断后的平均随访时间长达 11.5 年。

整体来看, 诊断乳腺癌患者中共 516 例因各种原因死亡,低脂饮食组相比对照组,自诊断乳腺癌后的 10 年全因死亡风险降低 22%(10 年生存率分别为 82% 和 78%,风险比 0.78,P=0.01)。

低脂饮食组更少患者死于乳腺癌,516 例名因任何原因死亡的乳腺癌患者中,低脂饮食组有 68 例死于乳腺癌,而对照组有 120 例死于乳腺癌,相差 1 倍。

低脂饮食的妇女,死于其他原因的概率也更低,特别是更少发生死于心脏病。在研究期间,64 例保持吃油腻饮食的女性死于心脏病, 而只有 27 名低脂饮食的女性死于心脏病。


平日保持低脂饮食,乳腺癌患者自诊断后的全因死亡风险降低 22%(图片来源:JAMA Oncology)

研究者指出,实施低脂饮食干预,可能改善乳腺癌患者的整体预后结局,但应注意,所带来的死亡风险降低,不全是因为低脂饮食对乳腺癌的影响,部分可归因低脂饮食可能改善了乳腺癌之外的其他原因导致的死亡风险。

Chlebowski 教授强调,这项研究传达出的关键信息是,健康人平日里保持低脂饮食,在一生中任何阶段都可能带来巨大的健康益处。

一些乳腺癌专家认为,这些发现,尤其对乳腺癌幸存者,有确实的指导价值。

" 健康饮食带来的生存获益,究竟是因为健康饮食改善了癌症发展,还是改善了患者整体健康所致,这不得而知。”纽约市 Lenox Hill 医院外科肿瘤学主任 Stephanie Bernik 博士说:“但是,不管怎么样,有一点很明确, 无论对于癌症幸存者还是普通人群,健康饮食都有可能延长预期寿命。”

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    2018-05-29 kafei

    了解一下谢谢

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