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J Bone Joint Surg Am:四个预测因素帮你鉴别莱姆病和化脓性关节炎

2016-06-27 MedSci MedSci原创

据发表于The Journal of Bone&Joint Surgery的一项新的研究结果显示,与莱姆病患者相比,化脓性关节炎儿童患者年龄通常小于2岁,短弧运动时会有疼痛,C-反应蛋白水平大于4 mg/L,存在发热史。研究人员对比了189名18岁以下的膝关节积液患者的病史、临床和实验室数据,这些患者已行关节穿刺术诊断为化脓性关节炎或莱姆病。结果显示,共有23名培养阳性的化脓性关节炎患者;26名培

据发表于The Journal of Bone&Joint Surgery的一项新的研究结果显示,与莱姆病患者相比,化脓性关节炎儿童患者年龄通常小于2岁,短弧运动时会有疼痛,C-反应蛋白水平大于4 mg/L,存在发热史。

研究人员对比了189名18岁以下的膝关节积液患者的病史、临床和实验室数据,这些患者已行关节穿刺术诊断为化脓性关节炎或莱姆病。

结果显示,共有23名培养阳性的化脓性关节炎患者;26名培养阴性的感染性关节炎患者;140名莱姆病患者。研究人员发现,33%被诊断为莱姆病的患者行手术切开引流是基于化脓性关节炎的诊断而实施的。行切开引流术的莱姆关节炎患者与未行外科手术的莱姆关节炎患者相比,其平均滑液白细胞计数、血白细胞计数、血沉、C-反应蛋白(CRP)的水平存在明显地差异。

多因素回归分析结果显示,感染性关节炎的独立预测因素包括短弧运动疼痛,发热史,CRP的大于4 mg/L,年龄小于2岁。不存在这些因素感染性关节炎的发生风险为2%,存在一个、两个、三个和所有因素的感染性关节炎的发生风险则分别为18%、45%、84%和100%。

该预测模型可用于鉴别化脓性关节炎膝和莱姆病。对于具有四个危险因素(短弧膝关节疼痛,CRP>4,发烧史和年龄<2岁)的患者应视需要接受紧急手术治疗的化脓性关节炎,而那些不存在这些危险因素的患者则可以进行观察,处于两者之间的患者,每增加一个危险因素,则感染性关节炎的风险相应增加。

原始出处:

Casey Tingle. Several independent risk factors for septic knee arthritis identified. Healio, June 26, 2016.

Baldwin KD, et al. Predictive Factors for Differentiating Between Septic Arthritis and Lyme Disease of the Knee in Children. J Bone Joint Surg. 2016;doi:10.2106/JBJS.14.01331.


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    2016-07-26 apoenzyme
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createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Jun 29 09:48:00 CST 2016, time=2016-06-29, status=1, ipAttribution=)]
    2016-09-17 1e10c84am36(暂无匿称)

    不错哦,会学到很多,喜欢梅斯医学文章

    0

  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Jun 29 09:48:00 CST 2016, time=2016-06-29, status=1, ipAttribution=)]
    2016-09-12 ylzr123

    关注学习。赞!好文探究。

    0

  6. 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encodeId=1b8612653194e, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Wed Jun 29 09:48:00 CST 2016, time=2016-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1439053, encodeId=cf4f143905343, content=<a href='/topic/show?id=5fef8e995c7' target=_blank style='color:#2F92EE;'>#莱姆病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87995, encryptionId=5fef8e995c7, topicName=莱姆病)], attachment=null, authenticateStatus=null, 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    2016-08-30 ylzr123

    好文,值得学习,赞!

    0

  7. 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