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Sleep Med:卒中患者易存在阻塞性睡眠呼吸暂停

2015-10-27 phylis 译 MedSci原创

背景:关于阻塞性睡眠呼吸暂停(OSA)和卒中位置的关系的文献报道结果不一致。研究者旨在急性缺血性卒中患者中,确定卒中位置和OSA的发生的关系;OSA的严重程度由睡眠呼吸暂停低通气指数(AHI),醒来的次数及缺氧检测和中枢和阻塞性肺疾病的发生来确定。方法:数据来源于一项进行OSA诊断和治疗的有效性评估的随机对照试验,这些患者患有急性缺血性卒中和短暂性脑缺血发作。根据脑影像学报告确定卒中位置:皮层下,

背景:关于阻塞性睡眠呼吸暂停(OSA)和卒中发生部位的关系的文献报道的结果不一致。研究者旨在在急性缺血性卒中患者中,确定卒中位置和OSA发生的关系;OSA的严重程度由睡眠呼吸暂停低通气指数(AHI)、醒来的次数及缺氧检测和中枢和阻塞性肺疾病的发生来确定。

方法:数据来源于一项进行OSA诊断和治疗的有效性评估的随机对照试验,这些患者患有急性缺血性卒中和短暂性脑缺血发作。根据脑影像学报告确定卒中位置:皮层下、脑干、小脑及血管区域。应用logistic回归分析急性卒中位置和多导睡眠监测的评估的OSA发生相关性,应用负二项回归评估与AHI指标的相关性。

结果:共有73个患者有完整的多导睡眠记录的数据和卒中位置的数据,58名(79%)患者存在OSA。在未校正模型中,没有卒中位置变量与OSA的发生和严重程度相关。相同的,在多变量模型中,卒中位置与OSA发生也不相关。

结论:这些结果显示OSA出现在大多数卒中患者中,并且卒中位置不能识别OSA发生的高风险患者。这些结果也表明OSA可能先于卒中出现。由于OSA整体发生率较高,对所有缺血性卒中患者应该强烈考虑进行多导睡眠监测。

原文出处:

Stahl SM, Yaggi HK, Taylor S,et al. Infarct location and sleep apnea: evaluating the potential association in acute ischemic stroke. Sleep Med. 2015 Oct.


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    2016-08-07 tomyang96
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content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 22:40:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
  5. 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content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 22:40:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
  6. 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encodeId=2d6416066e462, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Oct 29 06:33:00 CST 2015, time=2015-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41687, encodeId=7a7d4168e3a, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8b911658392, createdName=梦想天空, createdTime=Wed Oct 28 09:02:00 CST 2015, time=2015-10-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41611, encodeId=b97041611c3, 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  7. [GetPortalCommentsPageByObjectIdResponse(id=1696656, encodeId=87111696656da, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Sun Aug 07 06:33:00 CST 2016, time=2016-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1988992, encodeId=d433198899219, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, 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content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Oct 27 22:40:00 CST 2015, time=2015-10-27, status=1, ipAttribution=)]
    2015-10-28 梦想天空

    0

  8. 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    2015-10-27 sunlong28

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  9. 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    2015-10-27 sunlong28

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  10. 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    2015-10-27 sunlong28

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