Baidu
map

J Cosmet Dermatol:外用乙酰锌酮可有效改善光老化损伤

2021-08-21 MedSci原创 MedSci原创

乙酰姜酮(AZ)是来自姜的植物化学物质姜酮的衍生物,是一种新型化合物,据称具有抗衰老特性。发表于J Cosmet Dermatol的随机试验评估了乙酰姜酮在改善面部皮肤皱纹、发红、色素沉着和光老化方面

乙酰姜酮(AZ)是来自姜的植物化学物质姜酮的衍生物,是一种新型化合物,据称具有抗衰老特性。发表于J Cosmet Dermatol的随机试验评估了乙酰姜酮在改善面部皮肤皱纹、发红、色素沉着和光老化方面的作用。

研究纳入31名健康的参与者(年龄为44±7岁),以盲法方式随机分配到全脸涂抹1%的AZ或安慰剂(由载体基底霜组成),每天两次,共3次访问。使用面部图像分析摄影和软件评估光老化的迹象,包括皱纹、色素沉着和发红。

 

结果显示,与安慰剂相比,AZ组的平均皱纹严重程度(P=0.019;平均值=25.7%的变化)、总皱纹量(P=0.003;平均值=30.1%的变化)、色素强度(P=0.021;平均值=25.6%的变化)和发红强度(P=0.035;平均值=20.7%的变化)在8周内有明显下降。没有出现明显的瘙痒、燃烧或刺痛。两组在临床评估中的脱屑、红斑、色素沉着或色素沉着方面也没有明显的差异。

综上,该研究结果表明,与安慰剂相比,外用AZ可改善光损伤,减少皱纹、色素沉着和红肿强度的出现。乙酰锌酮在日常使用中具有良好的耐受性。

 

原始出处:

 

Simran Dhaliwal, et al., Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging. J Cosmet Dermatol. 2021 Jan;20(1):166-173. doi: 10.1111/jocd.13464.  

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1783635, encodeId=a7171e83635ad, content=<a href='/topic/show?id=f6c9511ec2' target=_blank style='color:#2F92EE;'>#CoSM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5117, encryptionId=f6c9511ec2, topicName=CoSM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=74c2229, createdName=tcm99hq, createdTime=Thu Nov 11 20:23:45 CST 2021, time=2021-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896883, encodeId=3c43189688380, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 29 07:23:45 CST 2022, time=2022-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388054, encodeId=2cb5138805405, content=<a href='/topic/show?id=18b3800914e' target=_blank style='color:#2F92EE;'>#老化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80091, encryptionId=18b3800914e, topicName=老化)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398187, encodeId=6558139818eba, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=)]
    2021-11-11 tcm99hq
  2. [GetPortalCommentsPageByObjectIdResponse(id=1783635, encodeId=a7171e83635ad, content=<a href='/topic/show?id=f6c9511ec2' target=_blank style='color:#2F92EE;'>#CoSM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5117, encryptionId=f6c9511ec2, topicName=CoSM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=74c2229, createdName=tcm99hq, createdTime=Thu Nov 11 20:23:45 CST 2021, time=2021-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896883, encodeId=3c43189688380, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 29 07:23:45 CST 2022, time=2022-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388054, encodeId=2cb5138805405, content=<a href='/topic/show?id=18b3800914e' target=_blank style='color:#2F92EE;'>#老化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80091, encryptionId=18b3800914e, topicName=老化)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398187, encodeId=6558139818eba, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=)]
    2022-01-29 一闲
  3. [GetPortalCommentsPageByObjectIdResponse(id=1783635, encodeId=a7171e83635ad, content=<a href='/topic/show?id=f6c9511ec2' target=_blank style='color:#2F92EE;'>#CoSM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5117, encryptionId=f6c9511ec2, topicName=CoSM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=74c2229, createdName=tcm99hq, createdTime=Thu Nov 11 20:23:45 CST 2021, time=2021-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896883, encodeId=3c43189688380, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 29 07:23:45 CST 2022, time=2022-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388054, encodeId=2cb5138805405, content=<a href='/topic/show?id=18b3800914e' target=_blank style='color:#2F92EE;'>#老化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80091, encryptionId=18b3800914e, topicName=老化)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398187, encodeId=6558139818eba, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1783635, encodeId=a7171e83635ad, content=<a href='/topic/show?id=f6c9511ec2' target=_blank style='color:#2F92EE;'>#CoSM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5117, encryptionId=f6c9511ec2, topicName=CoSM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=74c2229, createdName=tcm99hq, createdTime=Thu Nov 11 20:23:45 CST 2021, time=2021-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896883, encodeId=3c43189688380, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Sat Jan 29 07:23:45 CST 2022, time=2022-01-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388054, encodeId=2cb5138805405, content=<a href='/topic/show?id=18b3800914e' target=_blank style='color:#2F92EE;'>#老化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80091, encryptionId=18b3800914e, topicName=老化)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398187, encodeId=6558139818eba, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Mon Aug 23 14:23:45 CST 2021, time=2021-08-23, status=1, ipAttribution=)]

相关资讯

J Cosmet Dermatol:鱼源水解胶原蛋白可有效且安全改善皮肤老化的健康问题

胶原蛋白是人类皮肤的主要成分。随着年龄的增长,皮肤弹性和胶原蛋白的流失,导致皱纹的形成和皮肤外观的减少。

Baidu
map
Baidu
map
Baidu
map