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J Laryngol Otol:永久性和间歇性过敏性鼻炎患者中,鼻涂片嗜酸性粒细胞分析

2018-11-15 AlexYang MedSci原创

嗜酸性粒细胞是过敏性鼻炎致病机制的首要响应细胞。在非过敏性的鼻炎、过敏性鼻炎、嗜酸性粒细胞过多、阿司匹林过敏和鼻息肉中的细胞数据患者中,细胞的数目均增多。脱落鼻细胞学可以用来对过敏性鼻炎进行不同的诊断。最近,有研究人员评估了具有轻度、永久和间歇性过敏性鼻炎患者的鼻涂片中评估嗜酸性粒细胞。研究包括了60名患有过敏性鼻炎的患者和20名健康志愿者。患者分成间歇性和永久过敏性鼻炎2个小组,并且比较了鼻涂片

嗜酸性粒细胞是过敏性鼻炎致病机制的首要响应细胞。在非过敏性的鼻炎、过敏性鼻炎、嗜酸性粒细胞过多、阿司匹林过敏和鼻息肉中的细胞数据患者中,细胞的数目均增多。脱落鼻细胞学可以用来对过敏性鼻炎进行不同的诊断。最近,有研究人员评估了具有轻度、永久和间歇性过敏性鼻炎患者的鼻涂片中评估嗜酸性粒细胞。

研究包括了60名患有过敏性鼻炎的患者和20名健康志愿者。患者分成间歇性和永久过敏性鼻炎2个小组,并且比较了鼻涂片状态、嗜酸性粒细胞数目和总鼻症状评分。研究发现,60名过敏性鼻炎患者中的40名的鼻涂片是病理性的,并且要比对照具有更高的嗜酸性鼻细胞比例。在间歇过敏性鼻炎组中,平均的鼻嗜酸性评分比永久过敏性鼻炎组显著更高(p = 0.029)。另外,在永久过敏性鼻炎和间歇过敏性鼻炎患者中,鼻嗜酸性粒细胞评分和总鼻症状评分具有正相关关系(r = 0.652; p < 0.05)。

最后,研究人员指出,鼻涂片测试相对廉价、客观和容易操作,应该作为诊断调查的一部分。

原始出处:

Berkiten G, Aydogdu I, Kumral TL et al. Nasal eosinophilia in nasal smears of patients with persistent and intermittent allergic rhinitis. J Laryngol Otol. 5 Nov 2018.

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    2018-12-13 wxl882001

    学习一下

    0

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    2018-11-16 wxl882001

    了解一下

    0

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