Baidu
map

Nat Commun:多方面的免疫调控和组织向性临床细菌分离能够促进前列腺癌免疫治疗

2018-05-03 AlexYang MedSci原创

免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效,比如前列腺癌,且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象。最近,有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果。研究人员在研究中展示了一个来源于病人的前列腺特异性细菌,CP1,结合抗PD-1免疫治疗方法,能够在正位的MYC-和PTEN突变的前列腺癌模型中增加生存且减少肿瘤负担。CP1在尿道内特异性定殖并且能够在肿瘤上增殖

免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效,比如前列腺癌,且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象。最近,有研究人员假设选择组织特异性和免疫调控细菌能够具有促进这些免疫治疗的效果。

研究人员在研究中展示了一个来源于病人的前列腺特异性细菌,CP1,结合抗PD-1免疫治疗方法,能够在正位的MYC-和PTEN突变的前列腺癌模型中增加生存且减少肿瘤负担。CP1在尿道内特异性定殖并且能够在肿瘤上增殖,还不引起任何全身性的毒性。另外,CP1能够增加癌细胞、T细胞毒性、引起肿瘤浸润的激活的CD8 T细胞、Th17 T细胞、成熟树突细胞、M1巨噬细胞和NK细胞的免疫原性细胞的死亡。CP1同样能够减少肿瘤内调节T细胞和VEGF的免疫原性细胞的死亡。

最后,研究人员指出,从浸润的肿瘤中阻断CP1招募的T细胞能够抑制它的治疗效果。CP1是一个免疫治疗工具,并且阐释了组织特异性微生物是怎样能够增加肿瘤免疫原性以及如何使一种治疗抗性癌症类型对免疫治疗重新敏感。

原始出处:

Jonathan F. Anker, Anum F. Naseem, Hanlin Mok et al. Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy. Nat Commun. 23 April 2018.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (8)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-10-09 liuli5079
  2. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-08-31 liye789132251
  3. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-04 有备才能无患

    免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果.

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-04 张新亮1853311252142e2fm

    好文献学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-03 1e1b8538m79(暂无匿称)

    不错的文章值得拥有

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-03 有备才能无患

    免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果.

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2087337, encodeId=2c63208e33798, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7931272, createdName=liuli5079, createdTime=Tue Oct 09 10:04:00 CST 2018, time=2018-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1883008, encodeId=0bb518830081d, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Aug 31 03:04:00 CST 2018, time=2018-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599288, encodeId=92ba1599288b8, content=<a href='/topic/show?id=bfa7291e596' target=_blank style='color:#2F92EE;'>#免疫调控#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=29175, encryptionId=bfa7291e596, topicName=免疫调控)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f5018689307, createdName=yangcx0921, createdTime=Sat May 05 11:04:00 CST 2018, time=2018-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311926, encodeId=2997311926e7, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri May 04 13:03:29 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311829, encodeId=074b31182936, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Fri May 04 07:21:39 CST 2018, time=2018-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311734, encodeId=56ff311e34c6, content=不错的文章值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu May 03 22:52:03 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311721, encodeId=cd4b311e21fc, content=免疫检查点抑制剂对一些免疫反应迟钝的肿瘤并不十分有效.比如前列腺癌.且前列腺癌还包括了罕见的肿瘤浸润淋巴细胞现象.最近.有研究人员假设选择组织特异性和免疫调控细菌能够促进这些免疫治疗的效果., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu May 03 22:27:46 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311715, encodeId=6567311e15b7, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu May 03 22:17:55 CST 2018, time=2018-05-03, status=1, ipAttribution=)]
    2018-05-03 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

相关资讯

当AI遇上免疫疗法,下一代抗癌抗体呼之欲出

以抗PD-1/PD-L1的免疫检查点抑制剂为代表,肿瘤免疫疗法在近年来在全世界范围内,给癌症治疗带来了重大变革。在巨大成功之下,科研人员也正在开发下一代肿瘤免疫疗法,以提高它们的效果,延长它们的耐久。近日,利用人工智能(AI),我们在创新肿瘤免疫疗法的设计上,取得了可喜的进展。

盘点目前一些常见的免疫疗法

说起癌症,我们想到的多是化疗、放疗、手术等借助外部力量的治疗。但近几年,一种革命性的抗癌疗法正在兴起,并渐渐改变癌症治疗的格局,它就是免疫疗法。这是一种利用人体自身免疫系统对抗癌症的治疗。

一名“治不好”的癌症幸存者,带来了免疫疗法的新思考

当奥莉安娜(Oriana Sousa)提出要接受免疫疗法治疗时,许多医生回绝了她。医生们说,她的癌症很特别,免疫疗法治不好。医生们有充足的理由支持这个判断,但他们错了。这也让医生们开始反思,我们对免疫疗法的理解,或许在根源上就出现了偏差。罕见的癌症奥莉安娜是一名葡萄牙的心理学家,今年28岁。7年前,她发现身体出现了一些异样——几个月来,她不断感到疲惫和口渴,也出现了罕见的便秘与呕吐症状。当地的医

癌症"万能疫苗"又问世?这样做可避免30%癌症的发生

近日,有媒体报道《重磅!美国癌症疫苗研发成功,彻底根治率达97%》。那么,该癌症疫苗真的迎来“万能”时代了吗?

绝望的肿瘤:免疫疗法的两难

面对一些时日无多的病人,Sartor医生要问他们一个颇具挑战性的问题。这些病人大多是终末期前列腺癌患者。他们已经试过每一种标准疗法都不见效。而那些对某些肿瘤有神奇效果的新型免疫疗法药物,对前列腺癌的疗效仍不明确。Tulane医学院肿瘤学副院长Sartor医生,遇到的这个普遍的问题是:你临终前愿意尝试一下免疫疗法药物吗?微信图片_20180503085408.jpg▲Oliver Sartor博

免疫疗法可改善间皮瘤小鼠的存活率

近日,一项研究指出,两种癌症免疫治疗药物的联合使用能够显著延长侵袭性恶性间皮瘤小鼠模型的存活时间。来自马萨诸塞州总医院(MGH)的疫苗和免疫治疗中心(VIC)的一个研究小组将先前批准用于刺激骨髓移植之前干细胞产生的AMD3100(plerixafor)添加到在研药物VIC-008中使间皮瘤小鼠的生存时间加倍,而这种联合治疗的机制之一即是将免疫抑制性T细胞群体转变为肿瘤抑制性T细胞群体。

Baidu
map
Baidu
map
Baidu
map